the aim of this study was to investigate the effect of forced physical exercise with moderate intensity on alzheimer-induced amnesia in adult male rats. 48 male wistar- albino rats were randomly selected and assigned to 6 groups (n=8 per group): control, placebo (saline), drug-exercise, saline-exercise, exercise and exercise-drug. in this study, dicyclomine (16 mg/kg) was used to induce alzheim...

background: the cholinergic system plays an important role in learning and memory. administration of crocus sativus (saffron) or its constituent, crocin, facilitates the formation of memory. based on above findings, in the current study the effect of crocin in antagonizing retrograde amnesia induced by scopolamine, a cholinergic receptor antagonist, in rats was investigated by using shuttle box...

results the main pathological finding observed in the prostrate and seminal vesicle glands, using light microscope, revealed congestion in the connective tissue and vacuolization in the secretory units of epithelial cells and epithelium rupture at 50 and 100 µg/kg doses of bpa. ultrastructure study showed vacuolization of mitochondria, condensation of nuclei and disappearance of nucleus in the ...

Effect of pre-electroconvulsive shock (ECS) administration of calcium channel blockers (CCBs) like verapamil, diltiazem, nifedipine, nimodipine, flunarizine and cinnarizine on retrograde amnesia induced by ECS was examined using passive avoidance paradigm in rats. The groups (Gr 1-7) of adult, male Wistar rats received true ECS with CCBs (5mg/kg; i.p) or vehicle (10 ml/kg; ip) and other groups ...

introduction: the glutamatergic system plays an important role in learning and memory. administration of crocus sativus (saffron) or its constituent, crocin, facilitates the formation of memory. this research investigated the effect of crocin on antagonizing retrograde amnesia induced by ketamine, a glutamatergic receptor antagonist, in rats by shuttle box. methods:  male wistar rats were teste...

Background: Bisphenol A (BPA) has received attention in environmental and toxicological research due to its widespread effects in biological systems. While several anti-oxidants have been used in ameliorating BPA-induced toxicities in experimental animals, there is the scarcity of research information on the use of Gallic acid (GA) in protecting against BPA-induced toxicity. This study investig...