background: available drugs are not able to eradicate intracellular viral dna in patients with hepatitis b virus (hbv) infections. hbsag vaccine could induce immunity and subsequently eradicate hepatitis b virus in proportions of these patients. our aim was to evaluate the efficacy of hbsag as a mode of therapy in inactive carriers. materials and methods: forty two consecutive patients of inact...

OBJECTIVES We investigated whether long-term clinical outcomes such as disease progression or inactive hepatitis B virus (HBV) carrier state can be predicted by baseline factors in hepatitis B e antigen (HBeAg)-negative HBV infected patients with an elevated viral load. METHODS A retrospective cohort of 527 HBeAg-negative chronic HBV infected patients with an elevated viral load (HBV DNA ≥ 2,...

Aim. To investigate the relationship between hepatitis B e antigen seroconversion and the function of dendritic cells (DC) in patients with hepatitis B virus. Methods. The peripheral blood mononuclear cells (PBMC) from 21 chronic HBV patients in immune tolerance state, 23 patients in inactive HBsAg carrier state, and 10 healthy HBV-naive blood donors were incubated and induced into DC in presen...

background hepatitis b virus (hbv) is one of the most common chronic viral infections in the world. iran has a low to intermediate hbv prevalence and approximately 1.5 million people are living with hbv infection. the impact of hbv in iran is unknown and given the very low levels of alcohol consumption, this region provides an opportunity to examine the impact of isolated chronic hbv infection....

background: we aimed to explore whether maternal asymptomatic hepatitis b (hb) infection effects on pre-term rupture of membranous (prom), stillbirth, preeclampsia, eclampsia, gestational hypertension, or antepartum hemorrhage. methods: we searched the pubmed, scopus, and isi web of science from 1990 to feb 2015. in addition, electronic literature searches supplemented by searching the gray lit...

OBJECTIVE Rheumatoid factor (RF) positivity that may occur in a number of patients with hepatitis B (HBV) infection poses challenges in terms of differential diagnosis with rheumatoid arthritis (RA). On the other hand, antibodies to cyclic citrullinated peptide (anti-CCP) may prove to be an important marker for differential diagnosis of the two conditions. This study aimed to assess anti-CCP an...