background: endometrial secretion analysis is a non-invasive and promising method in evaluation of endometrial receptivity. objective: the aim of the present study was to assess the relationship between the success rate of ivf procedures and some endometrial secretion cytokines, including interleukin-1β (il-1β), tumor necrosis factor (tnf-α), interferon gamma-induced protein 10 (ip-10), and mon...

background: gonadotropin-releasing hormone (gnrh) plays essential roles in embryo implantation, invasion of trophoblastic tissue, and steroid synthesis in the placenta. objective: the aim of this study was to evaluate the effect of gnrh antagonist administration on pregnancy outcomes in early implantation period. materials and methods: in this retrospective study, 94 infertile women undergoing ...

background: gonadotrophin-releasing hormone (gnrh) agonist is used for controlling ovarian stimulation in assisted reproductive technology (art) cycles which has some benefits. objective: to compare the efficacy of two different formulations of gnrh agonist: short-acting and long-acting, for art protocols. materials and methods: in a prospective randomized study, one hundred women who underwent...

background: smoking has negative effects on reproductive process. exposing to cigarette smoking (passive smoking) may exert some effects as the direct smoking. objective: the aim of this study was to evaluate the correlation between ovarian response and passive smoking in women who underwent art cycles. materials and methods: one hundred-sixty patients who underwent icsi between 2000 and 2001 w...

background: vitamin d in complex with its receptor by regulating gene expression, endometrium immune response and stimulation of endometrium decidualization can be involved in implantation. so, it seems that the amount of vitamin d in follicular fluids (ff) may have an association with art success. objective: first, we intended to investigate the possible association between levels of follicula...

background: approximately one percent of current live births of the world are conceived via assisted reproductive technologies (art). objective:  the purpose of this study was to compare the developmental status of children born through assisted and natural conceptions at the age of five years. materials and methods:  in a retrospective cohort study, developmental status of 5 years old children...

a study was conducted to investigate the effect of follicular size (small,

background: conventional ivf and icsi are two common techniques to achieve fertilization. ivf has long been used for treatment of infertility, although it is not an effective treatment in severe male infertility. the use of icsi has been expanded in severe male factor and fertilization failure after ivf cycle. in spite of the widespread use of icsi in patients with non-male factor infertility, ...

Background: Mitochondria are the most aboudent and small essential organelles found in eukaryotic cells. These are semiautonomous organelles for the production of cellular ATP that through its various biochemical pathways. The primary pathway for ATP production is OXPHOS via the electron transfer chain (ETC) which is encoded by nuclear DNA and mtdna genomes. Mitochondria consist of double stran...

the main factors affecting pregnancy and implantation rates are uterine receptivity, embryo quality, and transfer efficiency. embryo transfer (et) is the last step of critically important procedure of in vitro fertilization (ivf) and probably the least successful step in assisted reproductive technology (art) treatment cascade; though simple in most of the cases, it may pose to be the most diff...