fecal calprotectin is released in colon by activated neutrophils. investigation of diagnostic application of determination of fecal calprotectin levels is considered by many researchers to compare between different colorectal diseases like irritable bowel syndrome (ibs) and inflammatory bowel diseases (ibd). due to the effect of nutrition habits on the inflammatory processes of bowel, the main ...

background: fecal calprotectin (fc) has been suggested as a noninvasive substitute marker to determine the degree of intestinal inflammation in patients with inflammatory bowel disease (ibd). the aim of this study was to compare fc levels in ibd and irritable bowel syndrome (ibs), to show its discriminative value and relationship with clinical disease activity in patients with ibd. materials an...

inflammatory myopathy is a paraneoplastic syndrome. inflammatory myopathy may be the first manifestation of underlying malignancy. it was reported in patients with colon cancer, breast cancer, ovarian cancer, lung cancer and non-hodgkin lymphoma. there are few reports regarding inflammatory myopathy in patients with gastric cancer. we want to present inflammatory myopathy as early manifestation...

background sepsis can be defined as the body’s response to an infection. sepsis in children remains a significant cause of morbidity and mortality worldwide. objectives this study focuses on the etiological factors, risk factors, and clinical characteristics of sepsis in neonate and pediatric patients. patients and methods a prospective study was conducted over a six-month period in the pediatr...

objective: heparin and enoxaparin possess anti-inflammatory properties. we compared the effects of these drugs on inflammatory biomarkers in patients with st-segment elevated myocardial infarction (stemi). method: thirty four patients with stemi randomly separated in two groups and received standard doses of heparin and enoxaparin. the serum concentration of serum amyloid a (saa), c-reactive pr...

procalcitonin (pct) is a precursor peptide for the hormone calcitonin and is frequently increased in overt sepsis. the aim of this study was to test diagnostic accuracy of procalcitonin among patients with positive systemic inflammatory response syndrome (sirs) in identifying sepsis. in this cross sectional study, from 563 patients with positive sirs admitted through the emergency department of...

background nephrotic syndrome (ns) characterized by a large amounts of protein into urine and a set of indications that include: protein in urine, low blood protein levels, high cholesterol levels, high triglyceride levels, and swelling. therefore, aim of this study was to investigate the relationship between prognosis of nephrotic syndrome and blood biomarkers level in children of arak city, i...

background procalcitonin (pct) levels are increased in sepsis. in most previously conducted research, pct levels were found to increase during septic shock. objectives the purpose of this study was to compare pct levels with crp and esr levels in children with systemic inflammatory response syndrome (sirs), sepsis, and septic shock. methods this cross-sectional study was conducted between decem...

background sepsis is one of the most important causes of morbidity and mortality in the intensive care units (icus). it is difficult to accurately differentiate sepsis from similar diseases rapidly. therefore, it becomes critical to identify any biomarker with the ability of differentiation between sepsis and nonsepsis conditions. the urokinase plasminogen activator receptor has been implicated...

the main inflammatory bowel disorders are including celiac disease (cd), inflammatory bowel diseases (ibd) and irritable bowel syndrome (ibs). celiac disease is a digestive and autoimmune disorder that can damage the small intestine and characterized by a multitude gastrointestinal (gi) and extra gi symptoms. ibd (including ulcerative colitis and crohn’s disease) is a group of inflammatory cond...