background: tumor associated antigens can be viably used to enhance host immune response.objectives: the immunomodulatory effect of biogenic selenium nanoparticles (senps) was compared between treated and untreated mice with crude antigens of 4t1 cells.materials and methods: female inbred balb/c mice (60) were injected by cancinogenic 4t1 cells causing breast cancer. after 10 days, all tumor be...

specific and non- specific cellular immune responses were studied in 20 amoebiasis cases and 10 controls. all the study cases and controls were indians living in varanasi, india. ten amoebic liver abscess cases were patients admitted to university hospital. ten non-invasive intestinal amoebiasis cases constituted the second study group. non-specific immune responses were studied using e-rosette...

twenty pregnant buffaloes, eight weeks before the expected calving date, were assigned into two homogeneous groups of 10 animals each, according to their season of lactation (2nd to 8th season of lactation); the first group (g1) were fed on a ration consisting of concentrate feed mixture (22% yellow corn, 35% cotton seed meal, 33% wheat bran, 4% rice bran, 3% molasses, 2% limestone and 1% sodiu...

background: occurrence of resistance against antibioticsand inadequate efficacy of some vaccines necessitates studies ofnatural immunostimulators in aquaculture. shrimps shell derivedfrom chitosan can be used as immune stimulators in fish.objectives: in this study, the effects of oral administration ofchitosan, derived from shrimp shell, on some immune responsesand disease resistance in cyprinu...

objective(s):gemifloxacin is a broad spectrum antibiotic and has shown excellent coverage against a wide variety of microorganisms. in this study, an attempt was made to evaluate the immunomodulatory potential of gemifloxacin in male swiss albino mice in vivo. materials and methods: three doses of gemifloxacin 25 mg/kg, 50 mg/kg and 75 mg/kg were used intraperitoneally (ip) for the evaluation o...

background and aims:il-22 is an α-helical cytokine.il-22 binds to a heterodimeric cell surface receptor composed of il-10r2 and il-22r1subunits.il-22r is expressed on tissue cells and it is absent on immune cells.il-22 and il-10 receptor chains play a role in cellular targeting and signal transduction to selectively initiate and regulate immune responses. the aim of this study was to investigat...

the objective of this research was to investigate the efficacy of dietary inclusion of probiotics primalac® and bactocell® and prebiotic fermacto® on broiler’s performance and immune response, individually or in combination. a total of 540 one-d-old male ross 308 broiler chicks were allocated into 6 experimental treatments with 6 replicates of 15 birds per replicate from 1 to 42 d of age. the b...

various commercial vaccines for immunization of broiler chickens against infectious bursal disease (ibd) are available, so it would be appropriate to compare the pathogenicity and immune response of chickens to these vaccines. in this study the pathogenicity and serologic response of four ibd vaccines, cloned d78®, bursine-2®, bursimune® and cevac gambo-l®, were evaluated in specific pathogen f...

the immune responses of mice immunized with ovalbumin (ova) together with killed l. major (klm) promastigotes as adjuvant were studied. three doses (5 × 107, 1 × 108 and 2 × 108) of klm combined with ova (100 mg) were injected into the groups of c57bl/6 mice. bcg and complete freund’s adjuvant (cfa) were used as control adjuvants. lymphocyte proliferation and antibody titers were determined, an...

objective(s):development of new generation of vaccines against leishmaniasis is possible because long-term protection is usually seen after recovery from cutaneous leishmaniasis. iscomatrix is particulate antigen delivery system composed of antigen, cholesterol, phospholipid and saponin. in this study, the role of iscomatrix bilayer composition made by different phase transition temperature (tc...