Tohoku University, Japan is developing a new hand-held land mine detection dual-sensor (ALIS) which is equipped with a metal detector and a GPR. ALIS is equipped with a sensor tracking system, which can record the GPR and Metal detector signal with its location. The Migration processing drastically increases the quality of the imaging of the buried objects.Evaluation test of ALIS has been condu...

Sex offenders are sometimes offered or required to undergo pharmacological interventions intended to diminish their sex drive (anti-libidinal interventions or ALIs). In this paper, we argue that much of the debate regarding the moral permissibility of ALIs has been founded on an inaccurate assumption regarding their intended purpose—namely, that ALIs are intended solely to realise medical purpo...

ALIS is a hand-held dual sensor developed by Tohoku University, Japan since 2002. Dual sensor is a general name of sensor for humanitarian demining, which are equipped with metal detector and GPR. ALIS is only one hand-held dual sensor, which can record the sensor position with sensor signals. Therefore, the data can be processed after data acquisition, and can increase the imaging capability. ...

The paper is partly based on research done for the EU-funded (IST2004-2.4.9) project ALIS (Automated Legal Intelligent System) on Intellectual Property Law. We describe the development process of the ALIS Intellectual Property ontology from both a legal and a technical perspective. We discuss the scope and the features of this IP ontology, the lessons learned, and the problems solved. This is d...

Abstaract. A novel simulation approach, called Adaptive Linked Importance Sampling (ALIS), is proposed to compute small failure probabilities encountered in high-dimensional reliability analysis of engineering systems. It was shown by Au and Beck (2003) that Importance Sampling (IS) does generally not work in high dimensions. A geometric understanding of why this is true when one uses a fixed i...

Toll-like receptors (TLRs) play a crucial role in several innate immune responses by regulating autophagy, but little is known about how TLR signaling controls autophagy. Here we demonstrate that p62/SQSTM1 is required for TLR4-mediated autophagy, which we show as selective autophagy of aggresome-like induced structures (ALIS). Treatment with LPS or Escherichia coli induced LC3(+) dot-like stru...

The efficiency of chemotherapy is often decreased by the development of resistance of cancer cells to cytostatic drugs. This phenomenon is in most cases caused by the activity of the various ABC transporters, multidrug-resistance (MDR) gene-encoded p-glycoproteins, that pump anticancer drugs out of the cells. The inhibition of the activities of the MDR proteins MDR1 and MRP was investigated via...

Figure 1. Avulsed extensor carpi radi-alis longus and brevis enthesis.