the purpose of this study was to investigate any association between iga deficiency (igad) and juvenile rheumatoid arthritis (jra) among iranian children. this case-control study was carried out on 83 children who were diagnosed as jra according to american college of rheumatology (acr) criteria; patients were admitted at the rheumatology clinic of children's medical center, (tehran). serum imm...

common variable immunodeficiency (cvid) and selective iga deficiency (sigad) are the most common primary antibody deficiencies. these two diseases may have coincidence in one family and sigad can progress to cvid which suggest common underlying genetic defects between sigad and cvid. this study was designed to find the prevalence of multiple cases in families of iranian patients with cvid or si...

selective deficiency of immunoglobulin a (iga) is the most frequent primary hypogammaglobulinemia. as some iga-deficient patients have iga antibodies in their plasma which may cause anaphylactic reactions, blood centers usually maintain a list of iga-deficient blood donors to prepare compatible blood components. in this study we determined the incidence of selective iga deficiency (sigad) in no...

GOALS To determine the prevalence and significance of immunoglobulin A (IgA) deficiency and partial deficiency in patients with celiac disease (CD). BACKGROUND Selective IgA deficiency is a common primary immunoglobulin deficiency and has a higher prevalence in patients with CD. The prevalence and significance of IgA deficiency and partial deficiency in patients with CD in the United States h...

BACKGROUND IgA deficiency causes false-negative IgA-based celiac serology results in patients with celiac disease. Using a case-finding strategy, we examined the prevalence of IgA deficiency, physician evaluation, and management of IgA deficiency during serological testing for celiac disease. METHODS We reviewed consecutive IgA-endomysial antibody (EMA) and serum IgA results from the laborato...

selective iga deficiency (igad) (serum iga concentration of pcr was used to type hla b, dr, and dq alleles in 29 iranian individuals with igad and 299 swedish individuals with igad. the results indicate a strong association with the hla b14, dr1 alleles in iranian subjects and hla b8, b12, b13, b14, b40, dr1, dr3, dr7, dq2 and dq5 alleles in swedish subjects. differences in hla association of i...

BACKGROUND AND OBJECTIVES IgA deficient patients are at risk of severe anaphylactic reaction on being transfused blood and blood products, and its prevalence varies in different parts of the world. No data are available from India. We did a blood donor survey to look for prevalence of IgA deficiency in north India. METHODS A sensitive enzyme linked immunosorbent assay developed in-house was u...

INTRODUCTION IgA deficiency (IgAD) is the most common primary immunodeficiency, which can cause frequent infections. The association of IgA deficiency with systemic lupus erythematosus (SLE) is very important because of the high morbidity and mortality rates of infections in patients with this disease. OBJECTIVES To study the prevalence of IgA deficiency in SLE patients from southern Brazil a...