background: high level radiation areas have been recognized on various parts of the earth. mahallat hot spring region is one of these areas. study of exposure in these areas can be helpful in investigating the effects of ionizing radiation. internal and external exposure to the staff was studied. materials and methods: used materials and instruments include: rss-112 ionizing chamber for environ...

abstract introduction:  this study was performed to compare the effects of low-dose interferon beta-1(cinnovex,30 mcg) and high-dose interferon beta-1(rebif,44 mcg) on the reduction of the number and size of plaques in magnetic resonance imaging (mri) in patients with multiple sclerosis (ms). methods and materials: this historical cohort study, which was performed in 2014 in sanandaj (western p...

introduction : methotrexate (mtx) is an anti folate drug that used in malignant and non malignant patients. the usage of high dose methotrexate was limited to patients with: osteogenic sarcoma, ewing sarcoma and lymphoma. the aim this study was to determine the toxicity or side effects of very high dose methotrexate (8-10 gr/m 2 /cycle). this study is the first study in iranian patients and one...

objective: acute inflammatory demyelinating peripheral neuropathy (guillain-barre-syndrome) is by far the most common cause of immune-medicated peripheral nervous system disease in children; with the near disappearance of poliomyelitis, gbs is responsible for the great majority of cases of acute flaccid paralysis. so far, in several controlled studies, corticosteroids, plasmapheresis and ivig h...

background: this study was performed to compare the effects of low dose interferon beta-1 (ifn-β-1) (cinnovex, 30 mcg) and high dose ifn-β-1 (rebif, 44 mcg) on the reduction of the number and size of plaques in magnetic resonance imaging (mri) in patients with multiple sclerosis (ms). methods: this historical cohort study, which was performed in 2014 in sanandaj (western part of iran). 43 ms pa...

given preliminary evidence of timed, sequential chemotherapy of high dose cytosine arabinoside the current study was initiated to assess the side effects and efficacy of this regimen in patients with newly acute myelocytic leukemia (aml). nineteen adults who referred to hematology-oncology and bone marrow transplantation (bmt) research center of tehran university of medical sciences were enroll...

high-dose extended-interval dosage (hded) regimen of aminoglycosides is now considered as the standard dosage strategy in sepsis. although safety and efficacy of this dosing regimen is well studied, but new experiments show increased the risk of resistance development associated with %t>mic less than 60% of the dosing interval following extended interval dosing. moreover, limited information is...

intensive induction therapy-in acute myeloid leukemia (aml), as in some other systemic malignancies- is a strategy fundamentally different from post-remission strategies. approaches like consolidation treatment, prolonged mainte nance, and autologous or allogeneic transplantation in the first remission are directed against minimal residual disease with a malignant cell population having survive...

background: the monte carlo (mc) method is not only used for dose calculations around brachytherapy sources but also for benchmarking treatment planning systems (tps) calculations. materials and methods: three 60co sources of gzp6 brachytherapy unit were simulated using mcnp4c mc code. the radial dose functions were calculated by mc method and gzp6 tps and were compared. results: there was a go...