background: sodium bicarbonate serum therapy is used for compensation bicarbonate lost and increasing blood ph in metabolic acidosis caused by severe anemia in patient with glucose-6-phosphate dehydrogenase (g6pd) deficiency. the aim of present study was comparison the effect of serum therapy using two different serums (serum with bicarbonate and without bicarbonate) on some renal and hematolog...

sixty-six children with g6pd deficiency were evaluated retrospectively to ascertain the clinical features, etiology, ultimate outcome and population at risk, the occurrence of jaundice in 18 neonates (group j) was, contrary to other countries, in the form of neonatal jaundice type ii. sepsis, prematurity, hypoxia and acidosis were associating factors. 77.8% of neonates had exchange blood transf...

In glucose-6-phosphate-dehydrogenase deficiency (favism), exposure to oxidant agents can trigger hemolytic crises. The intravenous administration of very high doses vitamin C was proposed as a treatment for severe coronavirus disease 2019 (COVID-19) pneumonia. Unlike low doses, (>6 gr daily) promote H2O2 formation, oxidation hemoglobin methemoglobin and, eventually, anemia in patients with f...

abstract background: sodium bicarbonate serum therapy is used for compensation bicarbonate lost and increasing blood ph in metabolic acidosis caused by severe anemia in patient with glucose-6-phosphate dehydrogenase (g6pd) deficiency. the aim of present study was comparison the effect of serum therapy using two different serums (serum with bicarbonate and without bicarbonate) on some renal and ...

Favism is an acute hemolytic anemia known to occur in susceptible individuals who ingest fava beans. Susceptibility to favism is conferred by a genetic deficiency in erythrocytic glucose-6-phosphate dehydrogenase (G6PD) activity. Although the fava bean pyrimidine aglycones, divicine and isouramil, have been implicated in the onset of favism in humans, the lack of a well-defined experimental ani...

favism is an acute hemolytic anemia which occurs in people who have (g6pd deficiency. in iran g6pd deficiency is prevalent in the coast of caspian sea. the main aim of our study was to investigate the prevalence of favism in mazandaran province in north of iran. our main source of data was the tiles of patients’ who had been hospitalized in three different children’s hospital in different citie...

.I T ORKERS IN ITALY,’ Israel”” and Americ&OU have shown that the V V gltmtathione ( GSH ) instability and decreased glucose-6-phosphate dehydrogenase ( C-6-PD ) activity, which are characteristic of primaquine sensitive imldividuals, are also present in persons who develop acute hemolytic anemia following ingestion of fava beans. The above authorsi ,:i, ii .12 have presented evidence that the ...

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an uncommon inherited enzyme deficiency characterized by hemolytic anemia, caused by the inability of erythrocytes to detoxify oxidizing agents such as drugs, infectious diseases, or fava bean ingestion. In this later case, the disorder is known as favism. The aim of the present report was to present a review of the literature in this disea...

By A. SZEINBERG, C. SHEBA, NINA HIRSHORN AND EVA B0D0NYI M OST acquired hemolytic anemias (with the exception of acquired idiopathic hemolytic anemia, incotnpatihle blood transfusions and Rh senzitization) and all cases of thalassemia show in this country a well defined ethnographic distribution. Only Jews originating from oriental and Mediterranean countries who have a da.rker consplexion and ...