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Sigma-1 Receptor Stimulation with PRE-084 Ameliorates Myocardial Ischemia-Reperfusion Injury in Rats
Background The sigma receptors are a relatively novel receptor group with respect to knowledge of their effect on health. Although the sigma-1 receptor agonist PRE-084 exhibits a cardioprotective effect in some studies, the benefits in cases of myocardial ischemia/reperfusion (I/R) are not clear. The aim of this study was to explore the mechanism of action and assess the effect of PRE-084 on my...
the present paper offers a postcolonial reading of two of the best novels by v. s. naipaul – half a life and the mimic men – in five chapters. the focus of this research is on different notions of postcolonial criticism and their application on the two novels as discussed from homi bhabha’s and frantz fanons points of view. having introduced the life and literary career of v. s. naipaul in th...
in the first part of this thesis we explored wetting and its dynamics for small droplets. first, we showed how a simple feature of water droplets on a surface, i.e. laplace pressure, can be exploited to build a micropump. we investigated capillary pumping in microchannels both experimentally and numerically. putting two droplets of different sizes at the in/outlet of a microchannel, will ge...
Malawi is a landlocked country, stretching over 94 084 square kilometres of land and 24 404 square kilometres of fresh water, whose economic backbone is agriculture. Malawi’s HIV positivity rate is estimated at 10.0% (Table 1).1 HIV prevalence varies widely by geographic regions, where it is 14.5% in southern Malawi, 7.6% in central Malawi and 6.6% in northern Malawi. Prevalence also differs by...
translation studies have become an accepted academic subject and books, journals and doctoral dissertations appear faster than one can read them all (bassnet and lefevere, 1990). but this field also brought with itself so many other issues which needed to be investigated more, in the heart of which, issues like ideology, ethics, culture, bilingualism and multilingualism. it is reported that ove...
We determined the influence of a new quinolone, DU-6859a, and two oral carbapenems, CS-834 and L-084, on the rat and mouse caecal microflora. The caecum-skin fistula-implanted rats and conventional mice were given oral antimicrobials at doses of 30 mg/kg bid for 5 days. DU-6859a generated a marked decrease in the numbers of caecal flora except for enterococci. CS-834 and L-084 had little impact...
تاثیر آموزش تفکر انتقادی به شیوه مباحثه بر روی مهارت درک متن یادگیرندگان انگلیسی به عنوان زبان خارجی
the purpose of the present study was to investigate the effect of instruction through debate on male and female efl learners’ reading comprehension, to examine the differences between the performance of male and female participants on the five dimensions of cctst including analysis, evaluation, inference, deductive reasoning, and inductive reasoning, and to examine the differences between male ...
the present study sought to investigate the impact of using mind-mapping technique instruction on female elementary efl learners reading comprehension; it also investigated their attitudes towards using mind-mapping technique as a tool to improve their reading comprehension. this study followed a quasi-experimental design with two intact groups as experimental, and control groups. the participa...
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