brucellosis is a major health problem in many parts of the world, particularly in the mediterranean and middle east. very few data on the frequency and diversity of haematological abnormalities occurring in brucellosis have been reported. in the present study 85 patients with brucellosis in imam khomeini hospital during 1997-2002 were investigated retrospectively to determine the haematological...

Osteoporotic fractures in elderly women are mainly due to postmenopausal bone loss but can sometimes be caused by a disabling haematological disease. We describe an 84-year-old woman suffering from multiple osteoporotic fractures as a manifestation of mast cell leukaemia. Mast cell leukaemia is a rare form of systemic mastocytosis with a poor prognosis and very few therapeutic options. Osteopor...

INTRODUCTION This study aimed to assess the kind of haematological abnormalities that are present in patients with mitochondrial disorders (MIDs) and the frequency of their occurrence. METHODS The blood cell counts of a cohort of patients with syndromic and non-syndromic MIDs were retrospectively reviewed. MIDs were classified as 'definite', 'probable' or 'possible' according to clinical pres...

Some haematological diseases are associated to an increased risk of thromboembolic events. We report a case of paroxysmal nocturnal haemoglobinuria (PNH) in which a cerebrovascular event represented the first clinical manifestation of disease. PNH is associated to thromboembolic events, generally of venous districts often involving unusual locations such as mesenteric vessels, sagittal veins, i...

We reported a 17-year-old adolescent with effusive constrictive pericarditis who presented with progressive heart failure. He was initially diagnosed to have hypereosinophilic syndrome with cardiac manifestation. Extensive workup showed no evidence of haematological malignancy or autoimmume disease. The constrictive pathology was later noted in echocardiography and cardiac catheterisation. Surg...

Medicinal plants are regarded as safe because of their natural origin, nevertheless, they can contain toxic substances that exert adverse effects. This study aims to evaluate acute and subacute toxicity Jatropha curcas seed oil using modified Lorke method 28 days repeated dosing grouped rats with normal saline -10, 300, 600 mg/kg body weight the oil. At end experimentation, haematological bioch...

Two patients are described with clinical and radiographic bronchiectasis which occurred after allogeneic bone marrow transplantation for haematological malignancy. Both had evidence of chronic graft versus host disease in other organs. Increased immunosuppression with corticosteroids resulted in clinical response, although both patients persisted with chronic mucopurulent sputum production and ...