background : cd117 is a thyrosin kinase receptor encoded by c-kit proto-oncogene. it is expressed during normal development in some tissues and also in a subset of neoplasia especially gastrointestinal stromal tumors   (gists). treatment with thyrosin kinase inhibitors (e.g., imatinib) is useful in cd117- positive gists. the goal of this study is to investigate the expression of cd117 in glial ...

background and objective: gliomas are the most common primary brain tumors. despite therapeutic advances, the majority of gliomas do not respond to either chemo or radiotherapy. cd117, the gene product of c-kit has been expressed in cells of glial tumors. because gastrointestinal stromal tumors (gists) that express cd117 respond dramatically to treatment with tyrosine kinase inhibitors, identif...

   Background and Objective: Gliomas are the most common primary brain tumors. Despite therapeutic advances, the majority of gliomas do not respond to either chemo or radiotherapy. CD117, the gene product of c-kit has been expressed in cells of glial tumors. Because gastrointestinal stromal tumors (GISTs) that express CD117 respond dramatically to treatment with tyrosine kinase inhibitors, ide...

Background & Objective: Gliomas are the most common type of primary intracranial tumors in adults. The expression of estrogen receptors varies in different grades of glial tumors, and some studies have suggested that this expression might have a prognostic value. It seems that estrogen receptor expression negatively correlates with the histological grade of gliomas. In the pres...

Pleomorphic xanthoastrocytomas (PXAs) are rare neoplasms comprising less than 1% of all astrocytic tumors, World Health Organization (WHO) grade II glial tumour.

SUMMARY Ten cases of cystic meningioma are reported and the literature is reviewed. The cyst formation with meningioma is rarely seen and are frequently associated with glial or metastatic tumor. The computerized tomography appearance of our cases also resembling glial and metastatic appearance of our cases also resembling glial and metastatic tumor. The incidence of microcystic and cystic cha...

BACKGROUND Glial tumors are most common brain tumors in our population. While the exact etiology and pathogenesis is unknown, the evaluation of current trends in the frequency and morphology of glial tumors is imperative to constitute better diagnostic and treatment protocols. Data pertaining to frequency and spectrum of glial tumors is scarcely available in our population. The aim of this stud...

Figure 1-MRI, sagittal SE 600/20. Intrasellar hypointense mass extending into sphenoid sinus (arrow). Pituitary gland elevated, optic nerve not involved. A 48 year old woman had an MRI examination of the brain which confirmed the clinical diagnosis of multiple sclerosis. Incidentally, a cystic mass was noted in the sella turcica. A pharyngeal soft tissue mass containing cysts was also shown (Fi...

suggest that brain tumors might result from occupation, dietary and other personal and residential exposures, but studies of cell phone use and power frequency electromagnetic fields have found little to support a causal connection with brain tumors; caveats remain though [8] . Previous studies have reported inconsistent results regarding the effect of anthropometric and lifestyle factors on th...