OBJECTIVE Cervical cancer is the second most common cause of death from cancer in women throughout the world. The aim of this study was to evaluate the cytotoxic activity of Kelussia odoratissima (K. odoratissima) extract associated with radiotherapy in cervical cancer cells (HeLa cell line). MATERIALS AND METHODS Different concentration of the extract (25-500µg/ml) was tested in HeLa cell li...

Kelussia odoratissima Mozaff. is a perennial aromatic herb, which grows up to 120 to 200 cm high. The flowers are 1 to 2 mm in diameter, all hermaphrodites and petals are yellow and produced in compound umbels. While this plant has lots of properties, the aim of this study is to overview its therapeutic, nutritive and industrial effects. This review article was carried out by searching studies ...

OBJECTIVE The present study aimed to evaluate the sedative and anxiolytic effects of the essential oils and hydroalcoholic extract of Kelussia odoratissima Mozaff. (K. odoratissima) in mice by utilizing an elevated plus maze. The chemical composition of its essential oil was also determined. METHODS The hydroalcoholic extract or essential oil fraction from this plant were administered intrape...

BACKGROUND Kelussia odoratissima Mozaff. is one of the newest genera of Umbelliferae which is represented by only one species. This sweet-smelling, self-growing monotypic medicinal plant is endemic to a restricted area in west of Iran and is locally called Karafse-koohi. The aerial parts of the plant are commonly used as a popular garnish and a sedative medicinal plant. There are several report...

The aim of the present study was to assess the effects of chronic and acute treatment of the essential oil (EO) of Kelussia odoratissima Mozaff. on the development of morphine tolerance and dependence in mice. Mice were rendered tolerant to and dependent on morphine by subcutaneous injection of morphine over a period of 5 days. Tolerance was assessed using the tail-pinch test and withdrawal sig...

Kelussia odoratissima Mozaff. is a sweet-smelling, self-growing plant which is traditionally consumed in Iran as a garnish. The aim of this project was study the structure of pollen grains in Kelussia odoratissima. Anthers of Kelussia were collected at full flowering stage from wild populations. Structure pollen grains were studied by scanning electron microscopy. The results showed that pollen...

BACKGROUND The aim of this study was to evaluate the anticancer potential of Kelussia odoratissima. Several in vitro and in vivo biological assays were applied to explore the direct effect of an extract and bioactive compound of this plant against breast cancer cells and its possible mechanism of action. MATERIALS AND METHODS K. odoratissima methanol extract (KME) was prepared, and MTT assay ...

Introduction: Hyperlipidemia is associated with increased risk of cardiovascular disease. Each type of medication works differently and has different types of side effects. Flavonoids are a group of polyphenolic compounds with antioxidant properties that help reducing the cardiovascular risk factors. Kelussia odoratissima is a flavonoid containing plant. Objectives: The aim of this study was in...

Due to the presence of polyphenols and phthalides in Kelussia odoratissima Mozzaf (Umbelliferae; K. odoratissima hereafter), this medicinal plant might be a robust in-feed additive to modulate lipid peroxidation in meat-type chickens. The present study evaluates antioxidative, antihyperlipidemic, and growth-promoting effects of K. odoratissima in meat-type chickens. In a 37-day trial (5-42 days...

due to the presence of polyphenols and phthalides in kelussia odoratissima mozzaf (umbelliferae; k. odoratissima hereafter), this medicinal plant might be a robust in-feed additive to modulate lipid peroxidation in meat-type chickens. the present study evaluates antioxidative, antihyperlipidemic, and growth-promoting effects of k. odoratissima in meat-type chickens. in a 37-day trial (5-42 days...