early identification of fetuses with chromosomal abnormalities enables health care providers to form an appropriate management plan for each patient. the main objective of this study was to determine the role of ultrasonography in screening and identifying fetuses at risk for chromosomal abnormalities. a retrospective review of 6480 patients from the obstetrics and gynecology ward of firouzgar ...

Background: To evaluate the association of increased fetal nuchal translucency( NT) and adverse pregnancy outcomes. Materials and Methods: In a prospective study, 2221 women who were conceived after Assisted Conception were investigated by sonography independent of multiplicity between 11 and 13 weeks' gestation. We performed 2899 NT examinations during the study period(21 March 2010 to 21...

Background: Prenatal diagnosis for Fetal Chromosomal anomalies currently relies on assessment of risk followed by a combination of biochemical and nuchal translucency. Trisomy 21 is the most common trisomy that is associated with intellectual disability. Pregnant women who receive a prenatal diagnosis of trisomy 21 currently have the option of continuing or terminating their pregnancy, but no f...

OBJECTIVE To assess the rate of fetal losses in twin pregnancies undergoing genetic mid-trimester amniocentesis. METHODS In the first part of this investigation, a retrospective cohort study compared a group of women . 32 years old with twin pregnancies who underwent amniocentesis with a similar group unexposed to amniocentesis. Data were compiled from January 1990 to March 2004 for patients ...

1. Case description A 23-year-old nulliparous woman was referred for fetal level II sonography owing to abnormal ultrasound findings, including skeletal anomalies and oligohydramnios at 20 weeks of gestation. Detailed evaluation of the fetus was difficult due to the absence of amniotic fluid. Thus, we infused normal saline into the amniotic cavity after amniocentesis for fetal karyotyping and f...

organic acidemias are the group of metabolic disorders which define by high anion gap metabolic acidosis, hypo or hyperglycemia & hyperammonemia.because of the severity of disease in children and its fatality in severe form of disease and also need for life long treatment, prenatal diagnosis is an important diagnostic tool.three approaches to prenatal diagnosis may be possible, including measur...

Background: The aims were to determine the diagnostic accuracy of ultrasound sonography in detecting major structural anomalies on all patients who conceived during a year of infertility treatment [assisted reproductive technology (ART) or non-ART treatments] at the Royan Institute, and to study the outcome of cases with nuchal translucency (NT) ≥ 95th centile in the first trimester of pregnanc...

OBJECTIVE We aimed to evaluate ductus venosus Doppler waveforms before and after amniocentesis in order to investigate any effect of amniocentesis on fetal myocardial hemodynamics. We also evaluated the umbilical artery, uterine artery and fetal mid-cerebral artery Doppler waveforms in order to investigate any relationship with ductus venosus Doppler changes. METHODS The study population cons...

An ultrasonic examination revealed a grossly distended fetal abdomen. Amniocentesis at 19 weeks' gestation showed raised amniotic fluid alphafetoprotein, a second band of specific acetylcholinesterase, and a fetal karyotype 47,XY,+18. The pregnancy was terminated and the necropsy examination showed absence of the urethra, grossly distended bladder, hydroureters, and congenital heart anomalies.