background gastrointestinal stromal tumors (gist) are the most common mesenchymal tumors of the gastrointestinal (gi) tract. they are usually c-kit positive and seen slightly more common in men. these tumors are seen in the gi tract from the esophagus to the anus with occasional invasion or metastasis. method in this retrospective study, we evaluated the prevalence of c-kit positive stromal tum...

introduction: numerous studies have investigated the prevalence, incidence and clinical manifestations of gastrointestinal stromal tumors (gists). however, little is known about gists in iran. this pioneer study focuses on description of 36 patients with gists in iran. methods: a database was created for 36 patients suffering from gist who were treated in loghman medical center and tehran cance...

gastrointestinal stromal tumors (gists) are uncommon tumors of the gastrointestinal (gi) tract that occur predominantly in adults. these tumors originated from cajal cells have positive mutations for kit (cd117) or platelet-derived growth factor receptor (pdgfra). gist especially multiple gists are very rare in children and lacking mutations in kit. we present a previously healthy 13 year- old ...

background gastrointestinal stromal tumors (gists) are potentially malignant tumors; however their behavior and response to treatment is dependent on the type of mutation and immunohistochemical expression of antigens. it is recommended to perform routine molecular and immunohistochemical tests in kit and platelet derived growth factor receptor alpha (pdgfra) molecules for making decision regar...

INTRODUCTION Gastrointestinal stromal tumors (GIST) are the most common mesenchymal tumors of the digestive tract. There is an increasing number of literature reports on synchronous occurrence of gastrointestinal stromal tumors and another malignancy of distinct etiology and evolution. The most reported cases include gastric synchronous occurrence of gastrointestinal stromal tumors and adenocar...

Gastrointestinal stromal tumor (GIST) is a rare cancer of the gastrointestinal tract, it occurred about 0.1-3.0% all neoplasms. Accounted 10% small-bowel tumors, and 10-15% sarcomas. Liver common hematogenous spread in GIST. However, metastasis to lymph nodes consider extremely routine node dissection for GIST was not recommended. Hence, we reported case series that metastasize along our experi...

Gastrointestinal Stromal Tumors (GIST) are the common mesenchymal tumors of gastrointestinal tract. They can display benign and malignant clinical behavior. The most common metastasis sites of malignant stromal tumor are liver, peritoneum, lung and bones. Metastasis to breast is extremely rare. Here, we present a case of GIST with liver, bone, lymph node and breast metastasis by reviewing the l...