background : gastric cancer is a common and lethal disease throughout the world. in iran with 7300 new cases annually, it is the first cause of cancer related death in both sexes. regarding the high incidence (10.5/100000 individuals) of gastric can­cer and priority of prevalence index in cancer management, in this study we tried to determine 1, 2-3 and 4-5 year point preva­lence of the disease...

introduction and aims: both observational and experimental studies have shown that higher selenium status reduces the risk of upper gastrointestinal cancers in selenium deficient populations. recent cancer registry data have shown very different rates of esophageal cancer (ec) and gastric cancer (gc) in four provinces of iran, namely ardabil, mazandaran, golestan, and kerman. the aim of this st...

introduction: the objective of the present study is to investigate the relationship between the familial history of digestive system cancers and development of gastric cancer. methods: in this case-control study conducted in 2012, 84 patients with a definite diagnosis of gastric cancer, diagnosed using endoscopy and pathological study of biopsies, were compared with 84 people with the same age ...

leptomeningeal carcinomatosis (lmc) from gastrointestinal cancer would be rare. a 56-years old man with complaint of dyspepsia and histopathologic examination of the biopsy specimens has shown: adenocarcinoma. at the end of adjuvant chemo radiation therapy, the patient has affected by headache and mild confusion. in cerebrospinal fluid (csf) cytology, a plenty of malignant cells have seen and u...

introduction: esophageal and gastric cancers are among the most common cancers in iran. usually survival of these cases is poor despite of treatment. here we studied outcome of these cases in our center to have an estimation of general prognosis of patients. methods: in this retrospective study, we reviewed the data of patient's files before treatment, including cancer stage at diagnosis, types...

background the number of patients with gastric cancer is growing worldwide. in iran (in 2009) of the 74067 new cases of cancer, 6886 were diagnosed as having gastric cancer. this study was conducted to investigate 5-year survival rate for gastric cancer in yazd province, central iran. methods in this descriptive study, the medical records of patients with gastric cancer were collected from the ...

background: combination chemotherapy is accepted as a high efficacy treatment for gastric cancer, whereas choice of standard treatment is unclear. multiple chemotherapeutic regimens have been used to achieve higher efficacy and lower toxicity. this study was designed to evaluate the treatment results of advanced gastric cancer with capecitabine and oxaliplatin regimen. subjects and methods : al...

abstract background: gastric cancer is one of the most common cancers in our country. recent studies have shown that adenocarcinoma of the cardia and distal stomach has increased in the past 25 years. however demographic data is lacking in this regard. methods: this study is a retrospective case series study. all records from 460 consecutive patients who were documented pathologically to have g...

background: the incidence rate of esophageal squamouse cell cancer (escc) in eastern part of golestan province in iran is among the highest ones in the world. in order to discover the factors interplay in high rate of escc incidence, several case-control and cross-sectional studies were established in this area.as a cohort study has priority in detecting risk factors of a disease, a 10-year pro...

background gastric cancer is the second most common cause of cancer death worldwide. lentinan was shown to induce apoptosis in gastric cancer cells and could be used for the treatment of gastric cancer. objectives in this study, we analyzed anticancer effect of lentinan, a fungal β-glucan, on the gastric adenocarcinoma cell line (ags). materials and methods we used the dna ladder and tunnel app...