compound possessing the acyl group in the 3-position of DHA nucleus 〔triacetic acid lactone (TAL)〕, the derivatives having the aroyl instead of the acyl group in the 3-position have never been synthesized. In order to investigate the activity which the carbonyl group in their side chain displays for of various primary amines and their antibacterial activity, some new DHA type derivatives posses...

Introduction In a previous paper [2] we described that Friedel-Crafts phenylation of the ringsystems (NPCl2)3-n(NSOCl)w (n = 1, 2) leads to a reaction at the sulphur atoms. Efforts to substitute a phosphorus-bonded chlorine atom failed however, even in the presence of an excess of A1C13. It has been demonstrated in phosphazene chemistry [3-6] that a PClAm group (Am = amino) is more reactive tow...

Due to the efficient product separation and catalyst immobilization, multi-phase catalytic systems are attractive for industrial applications. Nevertheless, it is usually difficult to decouple reaction and mass transfer kinetics such that the experimental determination of reaction kinetics is masked by mass transfer effects. A novel incremental identification methodology tailored to homogeneous...

One of the most common reactions in chemistry is the synthesis of ketones from acids1−4. First, the acid is changed into its chloride. Then the acid chloride reacts with an organometallic reagent or gives a FriedelCrafts type reaction in the presence of Lewis acids. These methods are very useful for most aliphatic acid halides and good yields can be obtained in this way. However, if this method...