this paper considers the multi-depot vehicle routing problem with time window in which each vehicle starts from a depot and there is no need to return to its primary depot after serving customers. the mathematical model which is developed by new approach aims to minimizing the transportation cost including the travelled distance, the latest and the earliest arrival time penalties. furthermore, ...

This paper proposes two new distance-constrained capacitated vehicle routing problems (DCVRPs) to investigate for the first time, and study potential benefits in flexibly assigning start and end depots. The first problem, DCVRP Fix is an extension of the traditional symmetric DCVRP, with additional service and travel time constraints, minimization of the number of vehicles and flexible applicat...

Depot-holders are women from the community who promote good health practice and use of clinics. They keep a stock of contraceptives and oral rehydration salts to supply other women and are paid some incentives. In 2003, the NGO Service Delivery Program (NSDP) introduced depot-holders in three types of urban area in Bangladesh as a pilot. This evaluation study was carried out to: (a) establish a...

The generalized multiple depot traveling salesmen problem (GMDTSP) is a variant of the multiple depot traveling salesmen problem (MDTSP), where each salesman starts at a distinct depot, the targets are partitioned into clusters and at least one target in each cluster is visited by some salesman. The GMDTSP is an NP-hard problem as it generalizes the MDTSP and has practical applications in desig...

cooperative object manipulation control of rigid-flexible multi-body systems in space is studied in this paper. during such tasks, flexible members like solar panels may get vibrated that in turn may lead to some oscillatory disturbing forces on other subsystems, and consequently produces error in the motion of the end-effectors of the cooperative manipulating arms. therefore, to design and dev...

The Vehicle Scheduling Problem (VSP) is the task of building an optimal set of rotations (vehicle schedule), such that each trip of a given timetable is covered by exactly one rotation. The restrictions and optimization criteria may differ from one problem setting to another. For multi-depot, multi-vehicle-type VSP for bus transit, each one-day rotation must end at the depot of start and is to ...

The poor design of interactive systems has been attributed to insufficient communication between developers and end users. Critical forms of communications include soliciting requirements and feedback on prototype systems. Our research develops a software lifecycle emphasizing feedback from end users and communication among end users, developers, and other stakeholders in a software development...

Hormonal deprivation therapy is well established for the treatment of locally advanced and metastatic prostate cancer, as well as the adjuvant treatment of some patients with localized disease. Long-acting gonadotropin releasing hormone (GnRH) agonists have become a mainstay of androgen deprivation therapy, due to their efficacy, tolerability, and convenience of use. One-month, 3-month, and 4-m...

In the recent decade, special attention is paid to reverse logistic due to economic benefits of recovery and recycling of used products as well as environmental legislation and social concerns. On the other hand، many researches claim that separately and sequential planning of forward and reverse logistic causes sub-optimality. Effective transport activities are also one of the most important c...