background: human chorionic gonadotropin (hcg) has been used as a replacement for the mid-cycle luteinizing hormone (lh) surge for several years. the recent arrival of recombinant dna technology has made recombinant hcg (rhcg) accessible. objective: to assess efficacy of rhcg compared to urinary hcg (uhcg) for triggering of ovulation and induction of final oocyte maturation in assisted reproduc...

routinely, a bolus of 5.000-10.000 iu human chorionic gonadotropin (hcg) is usedfor the final follicular maturation and ovulation as a standard method. hcg has thesame effect of luteinizing hormone (lh) with long half-life. it has the longlutheotrophic effect which increases the risk of ovarian hyper stimulation syndrome(ohss). recently, gonadotropin-releasing hormone agonist (gnrh-a) trigger h...

introduction: in vitro maturation and development of immature oocytes, as an artificial reproduction technique, is useful especially in women who are affected by cancer and polycystic ovary syndrome. despite using many types of in vitro media, an appropriate environment has not been reported yet. present study was designed to assess the effect of heated human follicular fluid (hhff), which is s...

Routinely, a bolus of 5.000-10.000 IU human chorionic gonadotropin (hCG) is used for the final follicular maturation and ovulation as a standard method. HCG has the same effect of luteinizing hormone (LH) with long half-life. It has the long lutheotrophic effect which increases the risk of ovarian hyper stimulation syndrome (OHSS). Recently, gonadotropin-releasing hormone agonist (GnRH-a) trigg...

the majority of cancer treatments are invasive. gonadal injuries cause reductions in fertility which results in lack of hope for conception in cancer patients and frustration for their partners. fortunately, current advancements in cryopreservation and transplantation sciences regarding fertility preservation lead to cryostorage of gonads and preservation prior to the onset of chemo- and radiot...

Since the pioneering days of in vitro fertilization, hCG has been the gold standard to induce final follicular maturation. We herein reviewed different pharmaceutical options for triggering of final oocyte maturation in ART. The new upcoming agent seems to be GnRHa with its potential advantages over hCG trigger. GnRHa triggering elicits a surge of gonadotropins resembling the natural midcycle s...

polycystic ovarian syndrome is a hetrogenous condition with a broad clinical and pathologic spectrum that may reflect the effects of diverse etiologic factors. polycystic ovarian syndrome is an abnormality in the maturation of the follicles which can result in abnormal composition of follicular fluid. by analysis and comparison of the biochemical composition of human follicular fluid in normal ...

Background: A safe, simple and cost-effective protocol is important goal in ART cycles. The aim of this prospective study was whether administration of low dose HCG in late follicular phase can be used clinically to replace gonadotropins administration in GnRH long protocol. Materials and Methods: 69 patients who were candidate for assisted reproductive technology (ART) enrolled the study and r...