Film coating is an essential unit operation in tablet manufacturing. Most tablet dosage forms in the market are film coated. The main purpose for coating of immediate release film dosage form is to provide colour identification, to enhance the stability, taste masking. It is also noted that film coating can improve the processibility and handling during pharmaceutical manufacturing and is the m...

it is possible to alter the permeability of ethyl cellulose membrane with certain materials such as surfactants. in this study the effect of surfactant concentration and different hlb values on the release rate of atenolol from ethyl cellulose-coated tablets was evaluated. the results showed that when the concentration of surfactant increased, the rate of drug release also increased. the kineti...

During the process development of coated tablets, knowledge on the formation and the location of film coating 'weak spots' is a key factor to the success of the process and the resulting product batch. It is understood that the performance of the product batch may be greatly limited, and often compromised, by weak spots on the tablet film coat. This study uses circular, biconvex tablets to inve...

In this study, Damar Batu (DB) − a novel biomaterial− is evaluated for its potential application in pharmaceutical coating. DB is a whitish to yellowish resin, characterized initially in terms of solubility, acid value, molecular weight (Mw), polydispersity index (Mw/Mn) and glass transition temperature (Tg). Neat plasticized films of DB are investigated for mechanical, water vapor transmission...

Opadry® II 1 Influence of Film Coating Process Parameters on the Gloss of Tablets Coated with Pigmented Aqueous Film Coating Formulations PURPOSE A common practice for enhancing the gloss of coated tablets is the application of a clear top-coat after applying a pigmented coating layer. In a recent study, substantial increases in tablet gloss were achieved using this multiple step approach.1 It ...

as we know sol-gel is one of the most important techniques for thin film preparation. in this paper, high transmission silica thin films have been prepared by dip-coating process from a new silicon-alkoxide solution. the prepared sol was stable for 45 days which is very important to characterize the coating process. the optical properties as a function of aging time, withdrawal rate, and heat t...

Spectral domain optical coherence tomography (OCT) has recently attracted a lot of interest in the pharmaceutical industry as a fast and non-destructive modality for quantification of thin film coatings that cannot easily be resolved with other techniques. Because of the relative infancy of this technique, much of the research to date has focused on developing the in-line measurement technique ...

in this study, damar batu (db) − a novel biomaterial− is evaluated for its potential application in pharmaceutical coating. db is a whitish to yellowish resin, characterized initially in terms of solubility, acid value, molecular weight (mw), polydispersity index (mw/mn) and glass transition temperature (tg). neat plasticized films of db are investigated for mechanical, water vapor transmission...

In this study, Damar Batu (DB) − a novel biomaterial− is evaluated for its potential application in pharmaceutical coating. DB is a whitish to yellowish resin, characterized initially in terms of solubility, acid value, molecular weight (Mw), polydispersity index (Mw/Mn) and glass transition temperature (Tg). Neat plasticized films of DB are investigated for mechanical, water vapor transmission...