abstract background: previous studies have shown that morphine consumption during pregnancy may delay embryo development or cause abnormal nervous system function. objective: the present study focused on the effect of maternal morphine consumption on development of placenta and blood corticosteron concentration in addictive pregnant mothers. materials and methods: 24 female rats, 170-200g weigh...

Background: Previous studies have shown that morphine consumption during pregnancy may delay embryo development or cause abnormal nervous system function .The most attention of research focuses on the embryo, whereas it was not attended to the placenta as an important organ which is affected by opioides. The present study focused on the effect of maternal morphine consumption on development of ...

objective: in previous studies it has been emphasized that the site of morphine action may be either in the embryo or the placenta. in the present study, we attempt to identify the site of morphine action on the fetal section of wistar rat placenta by using c14-morphine. materials and methods: in this study (experimental), female wistar rats (weights: 170-200 g) were mated with male rats and th...

Background: Experiments have shown that opioid drugs abuse during pregnancy can cause a delay in the development of the placenta. In mammals, the placenta is the most important channel for the exchange of Materialss between the maternal and fetal bloods. The present study investigates the time-dependent effect of the addiction duration of maternal morphine consumption during pregnancy. Material...

Dr. Flávio Ramalho Romero – Praça Amadeu Amaral 27 / 5o andar 01327-010 São Paulo SP Brasil. E-mail: [email protected] / [email protected] Training in microsurgical techniques is the first step to allow procedures in the central nervous system. One of them is the dissection of human placenta. Others include mannequin head, virtual reality environment, animal and cadaver dissections. The human ...

GLASSER, STANLEY R., CHARLES WRIGHT, AND ROBERT M. HIEYSSEL. Transfer of iron acrm the placenta and f&d membranes in the rat. Am. J. Physiol. 215(l) 2051-210. 1968.-The rate of accumulation and distribution of “gFe in the fetus, placenta, and accessory tissues was studied at different stages of gestation following iv injection of zgFe. There is a steady increase in percent of SgFe and in the to...

background: infection with parvovirus b19 may cause fetal losses including spontaneous abortion, intrauterine fetal death and non-immune hydropsfetalis. the aim of this study is to determine the frequency of parvovirus b19 in formalin fixed placental tissues in lost fetuses using real-time pcr method.   methods : in this cross-sectional study, 100 formalin fixed placental tissues with unknown c...

METHODS Female Wistar rats were exposed to filtered air (F) or to concentrated fine particulate matter (P) for 15 days. After mating, the rats were divided into four groups and again exposed to F or P (FF, FP, PF, PP) beginning on day 6 of pregnancy. At embryonic day 19, the placenta was collected. The placental structure, the protein and gene expression of TGFβ1, VEGF-A, and its receptor Flk-1...

BACKGROUND Sex-specific factors play a major role in human health and disease, including responses to environmental stresses such as toxicant exposure. Increasing evidence suggests that such sex differences also exist during fetal development. In a previous report using the resources of the New Hampshire Birth Cohort Study (NHBCS), we found that low-to-moderate in utero exposure to arsenic, a h...