BACKGROUND AND OBJECTIVES Acinetobacter spp. are important causes of nosocomial infections. They possess various antibiotic resistance mechanisms including extended spectrum beta lactamases (ESBLs). The aim of this study was to determine antibiotic resistance profile of Acinetobacter clinical isolates especially among ESBL-producing strains and to investigate the antimicrobial effects of oleo-g...

Ferula gummosa Boiss. (Apiaceae) is one of the natural plants of Iran. The whole plant, but especially the root, contains the gum resin "galbanum". A study of the comparative effects of galbanum gum and two standard binding agents--polyvinylpyrolidone and acacia--on characteristics of acetaminophen and calcium carbonate compacts was made. The Ferula gummosa gum was extracted and its swelling in...

Binders are agents employed to impart cohesiveness to the granules. This ensures the tablet remains intact after compression. The development of new excipients for potential use as binding agent in tablet formulations continues to be of interest. This is because different binding agents can be useful in achieving various tablet mechanical strength and drug release properties for different pharm...

background and objectives: acinetobacter spp. are important causes of nosocomial infections. they possess various antibiotic resistance mechanisms including extended spectrum beta lactamases (esbls). the aim of this study was to determine antibiotic resistance profile of acinetobacter clinical isolates especially among esbl-producing strains and to investigate the antimicrobial effects of oleo-...

Dormancy and germination response of Galbanum seeds (Ferula gummosa) under different hormonal pre-treatments cold stratification

In Iranian traditional medicine, there are some report regarding the anticonvulsant effect of Ferula gummosa Boiss. In this study, anticonvulsant activity, neurological deficits and lethality of the root acetone extract of this plant were evaluated in mice. The extract exhibited dose-dependent prevention of tonic seizures induced by pentylenetetrazole (ED50 = 154.4 mg/kg). However, the extract ...

OBJECTIVES Ferula gummosa Boiss is native to central Asia. This plant has traditionally been used in the treatment of many diseases. The antihypoxic and antioxidant activities of Ferula gummosa roots were investigated. MATERIAL AND METHODS 1,1-diphenyl-2-picryl hydrazyl radical (DPPH), nitric oxide and hydrogen peroxide scavenging activities, Fe2+ chelating ability, reducing power and hemoglo...

[This corrects the article on p. 26 in vol. 7, PMID: 26909039.].

Epilepsy is a brain disorder which affects about 50 million people worldwide. Ineffectiveness of the drugs in some cases and the serious side effects and chronic toxicity of the antiepileptic drugs lead to use of herbal medicine as a form of complementary and alternative medicine. In this review modern evidences for the efficacy of antiepileptic medicinal plants in Traditional Iranian Medicine ...

Four new farnesyl hydroxybenzoic acid derivatives, kuhistanols E-H (1-4), were isolated from the roots of the Uzbekistan medicinal plant Ferula kuhistanica. The structures of the new compounds were elucidated based on spectroscopic and chemical evidence.