mancozeb, a fungicide of a manganese-zinc ethylenebisdithio-carbamate (ebdc), was administered by gavage at doses of 200, 400, 600 and 800 mg/kg/day to female virgin mice for 30 days. the mice were autopsied on 31st day. mice were also treated with similar doses for a period of 30 days and the treatment was withdrawn for a further period of 30 days for reversible study. the mice were autopsied ...

in the present study, the effects of pregnant nmri mice restraint stress on the responsibility of their children to the behavioral properties of morphine, sulpiride and dextromethorphan were investigated in the f2 generation. twenty four pregnant nmri female mice (w: 25 g) were divided into the experimental and control groups (n = 12/group). animals in the experimental group were kept in the re...

carbosulfan (2,3-dihydro-2,2dimethyl-7-benzofuronyl [(dibutyl amino) thio] methyl] a carbamate insecticide and acaricide was administered orally at an effective dose of 48 mg/kg/day to albino mice for 5, 10, 20 and 30 days .control mice received similar quantities of olive oil. daily body weights were recorded and mice were sacrificed after 24 hours after the terminal exposure. the histologic e...

Neuropathic pain which is a chronic pain causes hyperalgesia due to peripheralm nerve damage.the relation between neuropathic pain and hyperalgesia and the response to treatment in case of somatic and inflammatory pain have been investigated previuosly.however the response of visceral pain in peripheral neuropathy and the possible gender differences in visceral pain response and gender differnc...

introduction: several investigations have indicated that dopamine d receptors could influence morphine 2 eward. the influence of olanzapine (a d dopamine receptor antagonist) on the morphine-induced conditioned 2 lace preference (cpp) in male and female mice was investigated in the present study. methods: the effects of olanzapine on the acquisition and expression of morphine cpp in male and fe...

Carbosulfan (2,3-dihydro-2,2dimethyl-7-benzofuronyl [(dibutyl amino) thio] methyl] a carbamate insecticide and acaricide was administered orally at an effective dose of 48 mg/kg/day to albino mice for 5, 10, 20 and 30 days .Control mice received similar quantities of olive oil. Daily body weights were recorded and mice were sacrificed after 24 hours after the terminal exposure. The histologic e...

Introduction: Several investigations have indicated that dopamine D receptors could influence morphine 2 eward. The influence of olanzapine (a D dopamine receptor antagonist) on the morphine-induced conditioned 2 lace preference (CPP) in male and female mice was investigated in the present study. Methods: The effects of olanzapine on the acquisition and expression of morphine CPP in...

objective: oximes are important materials in organic chemistry. synparamethyl benzaldehyde oxime (toloaldoxime) is structurally similar to other oximes, hence we have studied its effects on the neonatal and adult female balb/c mice reproductive systems in order to provide a platform for future studies on the production of female contraceptive drugs. materials and methods: in experimental study,...

bassia latifolia bud and cajanus cajan seed were evaluated for anti-fertility activity in mature female mice. anti-fertility activity was evaluated by observing the estrus cycle, body weight, wet weight of ovaries, steroidogenic enzymes, and substrates. bassia latifolia bud and cajanus cajan seed extract arrested normal oestrous cycle at dioestrous stage. the decrease in weight of ovary and ute...