A new nite element method for elliptic problems with locally periodic microstructure of length " > 0 is developed and analyzed. It is shown that the method converges, as " ! 0, to the solution of the homogenized problem with optimal order in " and exponentially in the number of degrees of freedom independent of " > 0. The computational work of the method is bounded independently of ". Numerical...

The tra-2 gene of the nematode Caenorhabditis elegans encodes a predicted membrane protein, TRA-2A, that promotes XX hermaphrodite development. Genetic analysis suggests that tra-2 is a negative regulator of three genes that are required for male development: fem-1, fem-2, and fem-3. We report that the carboxy-terminal region of TRA-2A interacts specifically with FEM-3 in the yeast two-hybrid s...

Abstract A Problem Solving Environment for the finite element method (FEM-PSE) is an application system to support users pursuing a career in the finite element analysis (FEA). There are two types of users associated with the FEA. One is analysis-user who uses application software of the FEM and the other is development-user who develops application software of the FEM. We used an abstraction t...

Thermo-hyperelastic problems at finite strains belong to a category of non-linear coupled problems that impose challenges on their numerical treatment. We present the weak-form for a 1-D coupled, stationary, thermo-hyperelastic system with constant or temperature-dependent material properties. The coupled system is discretized by a ‘monolithic’ high-order finite element method (p-FEM) based on ...

A selective smoothed finite element method (Selective S-FEM) is developed for dynamic 3D analysis of extremely large deformation of incompressible bio-tissues, using the simplest 4-node tetrahedron elements. In the present selective S-FEM, face-based Smoothed FEM (FS-FEM) and node-based Smoothed FEM (NS-FEM) are, respectively, used for the deviatoric and volumetric parts of the deformation of i...

Post-transcriptional control regulates many aspects of germline development in the Caenorhabditis elegans hermaphrodite. This nematode switches from spermatogenesis to oogenesis and is, therefore, capable of self-fertilization. This sperm-oocyte switch requires 3' UTR-mediated repression of the fem-3 mRNA. Loss of fem-3 repression results in continuous spermatogenesis in hermaphrodites. Althoug...

Male sexual development in the nematode Caenorhabditis elegans requires the genes fem-1, fem-2, and fem-3. The current model of sex determination portrays the FEM proteins as components of a novel signal transduction pathway, but the mechanisms involved in signaling through the pathway are not understood. We report the isolation of fem-2 cDNAs in a yeast two-hybrid screen for clones encoding pr...

Even when we look at stationary objects, involuntarily our eyes perform miniature movements and do not stand perfectly still. Such fixational eye movements (FEM) can be decomposed into at least two components: rapid microsaccades and slow (physiological) drift. Despite the general agreement that microsaccades have a central generating mechanism, the origin of drift is less clear. A direct appro...

The finite element methods (FEM) are important techniques in engineering for solving partial differential equations, but they depend heavily on element shape quality for stability and good performance. In this paper, we introduce the Adaptive Extended Stencil Finite Element Method (AES-FEM) as a means for overcoming this dependence on element shape quality. Our method replaces the traditional b...