severe overgrowth and tallness is very rare in human beings. the most common cause is gigantism due to the excessive secretion of the growth hormone, especially, before the closure of long bones’ epiphyseal growth plates. there are other rare disorders that are categorized on overgrowth syndromes. herein, we report an extremely rare, or even perhaps a unique, patient from iran. the clinical and...

Leiomyomas are common benign uterine tumors. However, the incidence of vaginal myoma is very rare and may be confused with a variety of vaginal tumors. We report a case of 43-year-old nulligravida who presented with a protruding painful vaginal mass for 7 days. The mass had initially appeared 3 years prior, as 2 to 3 cm that had not subsequently increased. However suddenly, there was rapid seve...

Figure 2: An aortogram revealed a giant aneurysm (arrow heads) arising from the aortic root. There was extremely slow contrast filling and washout of the giant aneurysm (A and B). A right ventricular angiogram demonstrated obstruction at the main pulmonary artery (C). Emergent surgery was performed because of the patient’s severe condition. After opening the pericardium, a giant aneurysm with d...

Giant intracranial aneurysms account for about 5 percent of all aneurysms, and are arbitrarily defined as having a diameter greater than 25 mm. These lesions, if left untreated, have an extremely poor natural history, with higher rates of morbidity and mortality than smaller saccular aneurysms. A retrospective review of untreatable giant aneurysms revealed an 80% risk of death or severe disabil...

giant cell glioblastoma is an extremely rare variant of glioblastoma (who grade iv) which is characterized by a predominance of bizarre, multinucleated giant cells. these tumors comprise of 0.8% of brain tumors and up to 5% of glioblastomas. in pediatric age group, these tumors are still uncommon with only around 53 published cases since 1952. here, we report a case of a 12-year old female pati...

Giant cell glioblastoma is an extremely rare variant of Glioblastoma (WHO grade IV) which is characterized by a predominance of bizarre, multinucleated giant cells. These tumors comprise of 0.8% of brain tumors and up to 5% of glioblastomas. In pediatric age group, these tumors are still uncommon with only around 53 published cases since 1952. Here, we report a case of a 12-year old female pat...

This paper looks at transgender identities and the law in the context of marriage. It particularly focuses on the role of language and definition in classifying transgendered individuals into a legal category. Two lines of cases in transgender jurisprudence are examined. The former cases decided the definition of ‘man’ and ‘woman’ on the basis of biological criteria while the latter cases held ...

A 60-year-old man presented with dysuria and elevated PSA (6.95 ng/ml). Needle biopsies of the prostate revealed well differentiated adenocarcinoma of Gleason's score 6. Prostatectomy and bilateral seminal vesiculotomy were performed. The material was totally cut into 16 preparations. The prostate showed well differentiated adenocarcinoma. The left seminal vesicle showed intraluminal monstrous ...

giant uterine leiomyomas are extremely rare neoplasms and are challenging both diagnostically and therapeutically. a 49-year-old premenopausal female presented at our department complaining of abdominal pain and distention for several years. ultrasound (us), color doppler us, abdominal computed tomography imaging after administration of contrast material, and abdominal magnetic resonance imagin...

We present an 89-year-old patient who was suffering from severe dyspnoea and mild dysphagia due to tracheal and esophagus compression by a giant goitre. The patient was euthyreotic. A total thyroidectomy was successfully performed. The pathology examination revealed fibrosarcoma G1, which is an extremely rare tumor of the thyroid.