This study evaluated the hypothesis that detection of Neisseria gonorrhoeae (GC) and Chlamydia trachomatis (CT) infections among HIV-infected active duty members of the U.S. Air Force would increase after expanding screening to include extragenital infections. Before and after the start of extragenital screening, urethral screening was positive for GC/CT in 2.9% and 1.9% of HIV-infected service...

BACKGROUND Although the Centers for Disease Control and Prevention does not recommend routine oropharyngeal and anorectal screening for Chlamydia trachomatis and Neisseria gonorrhoeae in the general population, they do recommend it for men who have sex with men. However, risk-based extragenital screening of men may not have been adopted at all college health centers, and existing research has n...

Bowenoid papulosis (BP) is a disease that mainly occurs in sexually active young adults. The patients present with multiple pigmented papular lesions with a verrucous surface on the anogenital area. Although extragenital BP is usually associated with concomitant genital involvement, a few cases of isolated extragenital BP have been reported. However, to our knowledge, BP of the nipple has not y...

1. Johnson TM, Saluja A, Fader D, Blum D, Cotton J, Wang TS, et al. Isolated extragenital bowenoid papulosis of the neck. J Am Acad Dermatol. 1999;41:867--70. 2. Fader DJ, Stoler MH, Anderson TF. Isolated extragenital HPVthirties-group-positive bowenoid papulosis in an AIDS patient. Br J Dermatol. 1994;131:577--80. 3. Rüdlinger R, Grob R, Yuan XY, Rus WS. Human papillomavirus35-positive bowenoi...

We report an unusual case of extragenital infection with Trichomonas vaginalis of the conjunctiva of a 32-year-old man. Only one other similar case has been reported in the English language literature. The present report reinforces the widening pathologic spectrum of trichomonads in humans, especially in the context of emerging extragenital infections.

Mycoplasma hominis is a fastidious micro-organism causing genital and extragenital infections. We developed a specific real-time PCR that exhibits high sensitivity and low intrarun and interrun variabilities. When applied to clinical samples, this quantitative PCR allowed to confirm the role of M. hominis in three patients with severe extragenital infections.

BACKGROUND AND OBJECTIVES Positive immunostaining for the tumor suppressor protein p16 is associated with the presence of mucosal or αsubtypes of human papillomavirus (HPV) in cervical and genital squamous cell carcinoma (SCC). The aim of this study was to determine whether p16 immunostaining is also associated with mucosal HPV in extragenital SCC. MATERIAL AND METHODS Paraffin sections of le...

Lichen sclerosus is an inflammatory skin condition characterized by inflammation of the papillary dermis that leads to white scarlike plaques. It occurs classically in the genitals but also has extragenital manifestations with a variety of clinical presentations including a bullous variant. The purpose of this review is to characterize extragenital bullous lichen sclerosus, suggest that it may ...

The female genital tract is an infrequent site of metastasis. Diagnosis of metastatic extragenital malignancy to the cervix on cervical-vaginal smear is extremely rare. We performed review of the database with diagnosis of malignant neoplasm metastatic to the uterine cervix between 2006 and 2011. These examples of metastatic extragenital malignancies to the cervix are lymphoma, and two colorect...

Lichen sclerosus is an uncommon inflammatory dermatosis with preferential involvement of the urogenital region. The extragenital involvement is uncommon and is characterized by small rounded macules or papules, pearly white in color. The coexistence of lichen sclerosus and scleroderma plaques in most cases with extragenital location has been reported in the literature. We report a case of liche...