iontophoresis of epinephrine for assessment of neuromuscular junction response is a new technique that can improve diagnose of neuromuscular dysfunction. the purpose of this study was to investigate the effects of iontophoresis of epinephrine on neuromuscular junction response. iontophoresis of epinephrine solution (1mg/ml), sodium chloride, calcium gluconate, epinephrine with sodium chloride a...

The effect of epinephrine on phosphatidate phosphohydrolase (PAP) activity of isolated human hepatocytes was studied. Epineprine inhibited the enzyme activity progressively at concentrations above 0.1 µM, reaching a maximum inhibition of 64.5% at 100 µM concentration. Inclusion of alprenolol, a β-receptor blocker, in the incubation mixture abolished the inhibitory effect of epinephrine on P...

Introduction: ghrelin is a potent orexigenic agent in rodents and humans. Some studies have shown that ghrelin participates in the adaptive response to weight loss and plasma concentration of ghrelin rises with dieting. On the other hand, weight loss and fasting is accompanied by increased levels of epinephrine and cortisol. In this study, we investigated the effects of epinephrine and corti...

Introduction: Several researches have reported that stress is able to inhibit the development of morphine tolerance via activating of Hypothalamic-Pituitary-Adrenal (HPA) axis. In the present study we tried to examine the effect of epinephrine, the product of adrenal medulla, on the development of morphine tolerance. Methods: Analgesic tolerance was induced by intrathecal (i.t.) injection of...

Incubation of rat hepatocytes with epinephrine inhibited alanine aminotransferase (ALT) (80%) and aspartate aminotransferase (AST) (53%) activities with no effect on lactate dehydrogenase (LDH) activity. Injection of epinephrine caused a progressive increase with time in hepatic LDH activity, being 52% at 24 h. Preinjection with propranolol eliminated the hormone effect and caused further ...

Abstract Background We investigated the role of epinephrine in prolonging localization lidocaine on oral mucosa and inhibiting its absorption blood rats. Methods used 7–8-week-old pathogen-free Wistar male rats (n = 128) for our study. divided them into control group administered with 14 C-labeled hydrochloride gel only study epinephrine. The medications were palatal amount mucosa, palatine bon...

Background: Duration of spinal anesthesia depends on the type of anesthetic agent, dosage and additive materials such as epinephrine, ephedrine and opioid. We compared the duration of spinal anesthesia with lidocaine 5% with or without epinephrine in addict and non-addict patients undergoing inferior limb fracture surgery. Methods: This single blinded randomized clinical trial was performed on ...

introduction lidocaine plus epinephrine is the most common anesthetic drug used in dentistry which has important cardiovascular side-effects like increase in blood pressure and cardiac arrhythmia. the goal of this study was to evaluat cardiovascular effects of one cartridge of 2% lidocaine + 1:80000 epinephrine. methods and materials 60 cases without any systemic diseases who had been admitted ...

abstract background: acute bronchiolitis is the most common form of lower respiratory tract infection in infancy. there are numerous contradictory reports regarding the efficacy of nebulized bronchodilators in the management of infants with acute bronchiolitis. this study was designed to compare the efficacy of nebulized epinephrine with salbutamol for treatment of the disease. methods: in a ra...