نتایج جستجو برای: embryonic stem cells (esc)

تعداد نتایج: 1542398  

Journal: :iranian biomedical journal 0
ماندانا بیگی بروجنی mandana beigi boroujeni مژده صالح نیا mojdeh salehnia مجتبی رضازاده ولوجردی mojtaba rezazadeh valojerdi مهدی فروزنده مقدم mehdi forouzandeh moghadam

background: the present study was designed to evaluate the homing potential of mouse embryonic stem cells (esc) treated with erythropoietin (epo) in hematopoietic organs such as spleen and liver after transplantation using morphological and immuno-histochemical techniques. methods: day-four embryoid body (eb)-derived cells were dissociated and re-plated in medium in the presence and absence of ...

نیک نژاد, حسن, گلچین, علی,

Background and purpose: The unique characteristics and potency of stem cells have attracted interest for their use in cell therapy. However, the use of these cells has some limitations and problems such as ethical issues. The aim of this study was to perform a systematic review on the use of embryonic stem cell for clinical therapy targets and investigating its advantages and limitations. Ma...

Background and Aim: Artificial gamete production from stem cells is a novel strategy for treatment of infertility. Among various stem cell sources, embryonic stem cells (ESC) can be considered as an appropriate source for in vitro formation of germ cells. In this study we evaluated the effect of BMP4 on proliferation and differentiation of mouse embryonic stem cells into primordial germ cells (...

Objective(s): In some previous studies, the extract of embryonic carcinoma cells (ECCs) and embryonic stem cells (ESCs) have been used to reprogram somatic cells to more dedifferentiated state. The aim of this study was to investigate the effect of mouse ESCs extract on the expression of some pluripotency markers in human adipose tissue-derived stem cells (ADSCs). Materials and Methods: Human A...

نوری دلویی, محمدرضا, تبریزی, مینا , سلمانی‌نژاد, آرش ,

Differentiated cells can change to embryonic stem cells by reprograming. Generation of induced pluripotent stem cells (iPSCs) has revolutionized the field of regenerative and personalized medicine. iPSCs can self-renew and differentiate into many cell types. iPSC cells offer a potentially unlimited source for targeted differentiation. Through the expression of a set of transcription factors, iP...

Leila Etemad

Backgrounds: A straight-forward way to identify whether a drug or environmental chemical can be harmful to unborn baby is to evaluate its effect on laboratory animals. All invivo methods need large number of animal and are therefore time consuming and expensive. However, the thousands of chemicals in need of testing, to reduce the spending of live animals, an assortment of in vitro assays has ...

Journal: :international journal of reproductive biomedicine 0
ali a movassagh-pour mojdeh salehnia ali a pourfatollah sayed m moazzeni

background: embryonic stem cells (esc) are pluripotent cells which have been used as a model to study the mechanism that control the embryogenesis and early mammalian development in vitro. the aim of this study was to isolate and produce embryonic stem cells from late blastocyst stage embryos in mice. materials and methods: blastocyst stage embryos from pregnant nmri mice were obtained and cult...

Journal: :international journal of reproductive biomedicine 0
maryam hosseinzadeh shirzeily parichehr pasbakhsh fardin amidi kobra mehrannia

background: recent publications about differentiation of stem cells to germ cells have motivated researchers to make new approaches to infertility. in vitro production of germ cells improves understanding differentiation process of male and female germ cells. due to the problem of using embryonic stem cells (esc), it’s necessary the mentioned cells be replaced with some adult multi-potent stem ...

Bahareh Sadegh Tabrizi , Behrooz Johari, Faezeh Maghsood, Majid Lotfinia, Mehdi Kadivar, Nastaran Mohammadi Ghahhari, Sara Parsania, Shirin Lak,

Background: Mesenchymal stem cells (MSCs) are important candidates for MSC-based cellular therapy. Current paradigm states that MSCs support local progenitor cells in damaged tissue through paracrine signaling. Therefore, study of paracrine effects and secretome of MSCs could lead to the appreciation of mechanisms and molecules associated with the therapeutic effects of these cells. This study ...

Journal: :international clinical neurosciences journal 0
mohammad salehi cellular and molecular biology research center, shahid beheshti university of medical sciences, tehran, iran. department of biotechnology, school of advanced technologies in medicine, shahid beheshti university of medical sciences, tehran, iran. saeed oraee-yazdani functional neurosurgery research center, shahid beheshti university of medical sciences, tehran, iran. stem cell biology department, stem cell technology research center, tehran, iran alireza zali functional neurosurgery research center, shahid beheshti university of medical sciences, tehran, iran. masoud soleimani hematology department, faculty of medical sciences, tarbiat modares university, tehran, iran

background: transplantation approaches are interventions currently available to apply to the devastating problem of spinal cord injury (sci). olfactory ensheathing cell (oec) and embryonic stem cell (esc) are considered to be promising therapeutic strategies . in this study, we compared the potential use of oecs and neurally pre-differentiated escs in contusion spinal cord. methods: oecs were h...

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