background: intraoperative radiation therapy (iort) technique is used to treat a surgically exposed tumor or tumor bed in the treatment of locally advanced intraabdominal, retroperitoneal, pelvic, thoracic, breast and soft tissue tumors. one way to perform iort is to use an existing linac and modify the treatment head using an applicator system. in this study the objectives were to design, and ...

Background: Breast conserving surgery (BCS) followed by radiotherapy (RT) has been widely accepted as the standard treatment in early stages of invasive breast cancer. The standard technique of RT includes whole breast irradiation (WBI). Additional tumor bed boost irradiation has also an important role in the local tumor control. But there are various controversial delivery methods. The aim of ...

Introduction: In the treatment of breast cancer, breast conserving surgery (BCS) and whole breast irradiation is a usual technique. The influence of lumpectomy boost following breast radiotherapy is apparent, but there are different delivery methods. This work intended to compare the dosimetric parameters of electron beams and photon beams for boosting irradiation in breast can...

background : the use of shorter radiotherapy schedules has an economic and logistic advantage for radiotherapy departments, as well as a high degree of patient convenience. the aim of this study is to assess the acute and short-term late toxicities of a hypofractionated radiotherapy schedule with a concomitant boost. methods : we enrolled 57 eligible patients as group a. these patients received...

Background:  After breast conserving surgery, most recurrences occur around the primary tumor site. This justifies the use of boost radiotherapy to the primary site of tumor. Surgical scar is not always a good surrogate for the location of the lumpectomy cavity. The aim of this study was to evaluate ultrasonic guidance for detection of the lumpectomy cavity after breast conserving surgery ...

PURPOSE The goal of this study was to evaluate the use of 3D ultrasound (3DUS) breast IGRT for electron and photon lumpectomy site boost treatments. MATERIALS AND METHODS 20 patients with a prescribed photon or electron boost were enrolled in this study. 3DUS images were acquired both at time of simulation, to form a coregistered CT/3DUS dataset, and at the time of daily treatment delivery. I...

PURPOSE The aim of this study is to determine overall survival, disease-specific survival and stoma-free survival after treatment of squamous cell carcinoma of the anus with chemoradiotherapy followed by brachytherapy or electron boost in a recent cohort of patients. METHODS Fifty-two patients (median age 62 years) were treated with radical chemoradiotherapy (mitomycin C, infusional 5-fluorou...

Environmental friendly solutions are becoming more prominent than ever as a result of concern regarding the state of our deteriorating planet. This paper presents a new DSP controller based Switching configuration of hybrid Distributed Energy Generators (DER) with a single input DC-DC Buck-Boost converter, based on their availability . This configuration allows the two sources to supply the loa...