background: 99mtc is a widely used radioisotope in nuclear medicine centers which is obtained by elution from mo-99/tc-99m generators. usually the generators are either supplied by the iran atomic energy agency or by private companies from foreign countries. in this study we have measured 99mo contamination in 99mtc elute from different generators in a period of one year. materials and methods:...

background: to investigate the status of the nuclear medicine (nm) centers in iran for the performance of dose calibrators, 18 out of 54 centers providing nm services in iran were randomly selected and inspected in 1997. in the first phase of the study the selected centers were inspected for performing of quality control (qc) tests of dose calibrators. the linearity of the activity response, pr...

background: technetium-99m radioisotope is the backbone of any nuclear medicine institute. this radioisotope is acquired by the elution of molybdenum-99/technetium-99m generator which emits 141 kev gamma ray and having 6.04 hour half-life. occasionally the contents of molybdenum-99 may mix up with elute, which may affect image quality and patients may receive higher doses than recommended. this...

We have reviewed quality control testing of dose calibrators and have analyzed the potential for error. The uncertainty in half-lives of reference sources can lead to inaccurate assessment of the accuracy and constancy in dose calibrator performance. Molybdenum-99 contamination of '"Tc used as a reference source can appear as a nonlinear response of the dose calibrator. The useful life of a ref...

UNLABELLED This investigation examined the accuracy of dose calibrator activity measurement of the beta-emitting radiopharmaceutical (90)Y-ibritumomab tiuxetan. METHODS Five different facilities independently measured (90)Y in a 10-mL syringe geometry with 30 dose calibrator models from 3 different manufacturers. The activities ranged from 81.4 MBq (2.2 mCi) to 1,406 MBq (38 mCi) over the vol...

OBJECTIVE The present study was aimed at evaluating the viability of replacing (18)F with (99m)Tc in dose calibrator linearity testing. MATERIALS AND METHODS The test was performed with sources of (99m)Tc (62 GBq) and (18)F (12 GBq) whose activities were measured up to values lower than 1 MBq. Ratios and deviations between experimental and theoretical (99m)Tc and (18)F sources activities were...

UNLABELLED The performance and measurement of (90)Y with a dose calibrator has always been a key point of several international recommendations, specifically in the case of the radiopharmaceutical (90)Y-ibritumomab tiuxetan, among other applications, used in the treatment of non-Hodgkin lymphoma. The objective of the present work was to examine in detail some important sources of geometric erro...

This study investigated the feasibility of quantitative accuracy and harmonized image quality in Zr-PET/CT multicentre studies. Methods: Five PET/CT scanners from 3 vendors were included. Zr activity was measured in a central dose calibrator before delivery.Local activity assays were based on volume as well as on the local dose calibrator. Accuracy and image noise were determined from a cross c...