background: colorectal carcinoma is the third most common cause of death in iran. this study was performed in order to determine the appropriate distal clearance margin (dcm) for resection of rectal cancer in patients who undergo neoadjuvant chemoradiotherapy for sphincter preserving procedure. materials and methods: this was a cross-sectional study conducted in shahid faghihi hospital of shira...

Background: Colorectal carcinoma is the third most common cause of death in Iran. This study was performed in order to determine the appropriate distal clearance margin (DCM) for resection of rectal cancer in patients who undergo neoadjuvant chemoradiotherapy for sphincter preserving procedure. Materials and Methods: This was a cross-sectional study conducted in Shahid Faghihi Hospital of Shira...

We used 16S rRNA gene tag pyro sequencing to examine the biogeography of bacterial and archaeal community composition in the deep chlorophyll maximum (DCM) of the South Pacific Gyre (SPG), the largest and most oligotrophic region of the world ocean. Dominant DCM bacterial taxa, including Prochlorococcus, SAR11, SAR406, and SAR86, were present at each sampled site in similar proportions, althoug...

BACKGROUND The choice of operation for tumours at or around the gastro-oesophageal junction remains controversial with little evidence to support one technique over another. This study examines the prevalence of margin involvement and nodal disease and their impact on outcome following three surgical approaches (Ivor Lewis, transhiatal and left thoraco-laparotomy) for these tumours. METHODS A...

BACKGROUND Previous studies have not identified how to determine the optimal distal margin in rectal cancer based on histopathological diagnosis. We examined the surgical distal resection margin from a histopathological viewpoint. METHODS We enrolled 629 patients. The type of distal spread was evaluated, and the maximum length of distal spread was measured using a micrometer. RESULTS The fr...

BACKGROUND The 11C-acetate positron emission tomography can estimate myocardial oxidative metabolism, but previous studies have only evaluated small populations and the difference between ischemic (ICM) and idiopathic dilated cardiomyopathy (DCM) has not been fully investigated. The present aims were to evaluate global and regional myocardial oxidative metabolism in a well-characterized, large ...

BACKGROUND Low recurrence rates and long term survival are the main therapeutic goals of rectal cancer surgery. Complete, margin- negative resection confers the greatest chance for a cure. The aim of our study was to determine whether the length of the distal resection margin was associated with local recurrence rate and long- term survival. PATIENTS AND METHODS One hundred and nine patients,...

Purpose: Resection margin status is considered one of the few surgeon-controlled parameters affecting prognosis in pancreatic ductal adenocarcinoma (PDAC). While studies mostly focus on resection margins pancreatoduodenectomy, little known about their role distal pancreatectomy (DP). This study aimed to investigate DP for PDAC. Method: Patients who underwent PDAC between October 2004 and Februa...