BACKGROUND Disseminated leishmaniasis is an emerging infectious disease, mostly due to L. braziliensis, which has clinical and histopathological features distinct from cutaneous leishmaniasis. METHODS In the current study we evaluated the in vitro production of the cytokines IFN-gamma, TNF-alpha, IL-5 and IL-10 by peripheral blood mononuclear cells (PBMC) from 15 disseminated leishmaniasis an...

purpose : to introduce a case of cutaneous and lid leishmaniasis in an immune suppressed woman case report : we report an unusual clinical course of old world cutaneous leishmaniasis (owcl) in an immune suppressed 51 years old women recipient of kidney transplant. she developed disseminated cutaneous leishmaniasis (dcl) with bilateral upper and lower eye lids lesions. antimoniate compounds were...

conclusions although dcl is rare, physicians should mind its occurrence it in any immunocompromised patient with diffuse cutaneous ulcers refractory to treatment. case presentation here is the report of a 43-year-old man referred to infectious diseases clinic in boo-ali hospital (zahedan city, southeastern iran) because of multiple chronic ulcers for five months. during the time, he had been vi...

Background.  Disseminated leishmaniasis (DL) is an emerging clinical form of American tegumentary leishmaniasis (ATL) that occurs mainly in Northeastern Brazil. This study describes 18 cases where DL has not yet been reported. Methods.  Disseminated leishmaniasis cases were extracted from ATL recorded cases between 1987 and March 2015. Disseminated leishmaniasis identification was based on ≥10 ...

a 5-month old puppy with muco-cutaneous lesions in the chin, around lips and eyes was exam­ined physically and microscopically for leishmaniasis. muco-cutaneous lesions containing a large num­ber of amastigotes of leishmania spp. were observed . amastigotes were also detected in liver and spleen of the puppy. the animal was positive with dipstick rk39 kit and high level of anti- leishmania anti...

The clinico-pathological and immunological findings in eight patients from Bahia, Brazil with disseminated cutaneous leishmaniasis are described. This condition differs from anergic diffuse cutaneous leishmaniasis (DCL) and from classical American cutaneous leishmaniasis (ACL). The number of lesions in these patients ranged from 75 to 800 and were characterized by papules and an acneiform type ...

BACKGROUND Co-infection of leishmaniasis and HIV is increasingly reported. The clinical presentation of leishmaniasis is determined by the host immune response to the parasite; as a consequence, this presentation will be influenced by HIV-induced immunosuppression. As leishmaniasis commonly affects the skin, increasing immunosuppression changes the clinical presentation, such as in post-kala-az...

background cutaneous leishmaniasis is an endemic infectious disease in iran caused by flagellated protozoa. the most common cause of cutaneous leishmaniasis is l. major. we report a case of disseminated cutaneous leishmaniasis after renal transplantation. a 50-year old man received renal transplantation three months ago for diabetes mellitus-associated renal failure. before renal transplantatio...

The wide variety of Leishmania species responsible for human American cutaneous leishmaniasis combined with the immune mechanisms of the host results in a large spectrum of clinical, histopathological, and immunopathological manifestations. At the middle of this spectrum are the most frequent cases of localized cutaneous leishmaniasis (LCL) caused by members of the subgenera Leishmania and Vian...

Cutaneous leishmaniasis (CL) is a parasitic disease, which is hyperendemic in Isfahan, usually caused by L.major and L.tropica. Herein we report a patient with post-mastectomy lymphedema on right upper limb accompanying with the lesions of cutaneous leishmaniasis on the right and left forearms. Following radiotherapy, the lesions on the limb with lymphedema were disseminated. But the lesions on...