The effects of depot formulations of the luteinizing hormone-releasing hormone (LHRH) agonist Decapeptyl (25 microg/day) for 30 days or LHRH antagonist Cetrorelix pamoate (100 microg/day) for 30 days and daily injections of 100 microg of Decapeptyl for 10 days on the expression of mRNA for pituitary LHRH receptor (LHRH-R) and the levels of LHRH-R protein were evaluated in rats. Serum sex steroi...

BACKGROUND Gonadotropin-releasing hormone (GnRH) is a reproductive key hormone. The GnRH analogues are widely used in in vitro fertilization and treatment of sex hormone-depended cancers induced by the materials used in chemotherapeutic agents. OBJECTIVE The aim of this study is to evaluate the effects of cyclophosphamide and decapeptyl (analogues of GnRH) on histomorphometry and stereology o...

BACKGROUND To compare efficacy of simvastatin with GnRHa (Decapeptyl 3.75 mg) on endometriosis-related pains following surgery for endometriosis. MATERIAL/METHODS Sixty women with pelvic endometriosis, after laparoscopic diagnosis and conservative laparoscopic surgery, were treated with either simvastatin (n=30) for 16 weeks or Decapeptyl (n=30) every 4 weeks for 4 doses. RESULTS Using VAS,...

Kung et al authored a valuable article entitled “Luteal phase support with decapeptyl improves pregnancy outcomes in ICSI with basal FSH >8 mIU/mL or mature oocytes 3”. This retrospective study enrolled 240 patients who underwent intracytoplasmic sperm injection (ICSI). One hundred and forty-seven patients were in the decapeptyl group and 93 patients were in the control group. The authors inves...

background: gonadotropin-releasing hormone (gnrh) is a reproductive key hormone. the gnrh analogues are widely used in in vitro fertilization and treatment of sex hormone-depended cancers induced by the materials used in chemotherapeutic agents. objective: the aim of this study is to evaluate the effects of cyclophosphamide and decapeptyl (analogues of gnrh) on histomorphometry and stereology o...

Introduction and Objective: Bilateral bleeding found over healthy eyes, in healthy pubertal females, that is cyclic and concomitant with menses, is a very rare event. Rarer is its association with cyclic epistaxis and cyclic bleeding from ears and skin bleeding. We present a series of such cases and a trial to diagnose and manage them. Those cases remained undiagnosed for years. We also present...

The direct antitumoral effects of gonadotropin-releasing hormone (GnRH) analogues on breast tumors have been surmised from clinical observations and in vitro studies. The present study aimed to determine the effects of the GnRH agonist [D-Trp6]GnRH (Decapeptyl) on steps of experimental mammary carcinogenesis, and the mechanisms, other than the chemical castration, involved. We chose a recent mo...

Left ventricular thrombi seen by ventriculography are a significant risk factor for stroke in open-heart surgery. Nature of deposits in a tubular membrane oxygenator after prolonged extracorporeal circulation: a scanning electromicroscopy study. the microcirculation of the cerebral cortex of dogs subjected to pulsatile and non-pulsatile flow during extracorporeal circulation. In: A propos du de...

background: gonadotrophin-releasing hormone (gnrh) agonist is used for controlling ovarian stimulation in assisted reproductive technology (art) cycles which has some benefits. objective: to compare the efficacy of two different formulations of gnrh agonist: short-acting and long-acting, for art protocols. materials and methods: in a prospective randomized study, one hundred women who underwent...