نتایج جستجو برای: d4=9

تعداد نتایج: 72  

Journal: :Physical chemistry chemical physics : PCCP 2016
Oliver Flender Mirko Scholz Johannes R Klein Kawon Oum Thomas Lenzer

We present an ultrafast UV-Vis-NIR transient absorption study of the donor-acceptor solar-cell dye D49 in diisopropyl ether, THF and acetonitrile, as well as on mesoporous Al2O3 and TiO2 thin films. Photoexcitation at 505 nm initially populates the first electronically excited state of the dye having significant intramolecular charge transfer character ("S1/ICT"). On Al2O3 and in the three orga...

2017
David Drummond Mélissa Baravalle-Einaudi Guillaume Lezmi Shamila Vibhushan Marie-Laure Franco-Montoya Alice Hadchouel Jorge Boczkowski Christophe Delacourt

BACKGROUND Fetal determinants of airway function, such as in utero exposure to maternal cigarette smoke (CS), may create a predisposition to adult airflow obstruction and chronic obstructive pulmonary disease (COPD) in adulthood. It has been suggested that active smoking in adolescence and preexisting airflow obstruction have synergistic deleterious effects. OBJECTIVE We used a mouse model to...

Journal: :Protein engineering 2001
G W Rudgers T Palzkill

Protein-protein interactions are involved in most biological processes and are important targets for drug design. Over the past decade, there has been increased interest in the design of small molecules that mimic functional epitopes of protein inhibitors. BLIP is a 165 amino acid protein that is a potent inhibitor of TEM-1 beta-lactamase (K(i) = 0.1 nM). To aid in the development of new inhibi...

2018
Marco Puthenparampil Francesca Rinaldi Lisa Federle Chiara Cazzola Paola Perini Paolo Gallo

Background The cause and clinical significance of the transient decrease in platelet (PLT) count observed in relapsing remitting multiple sclerosis (RRMS) during alemtuzumab administration remain undefined. The aim of this study was to analyse the kinetics and clinical relevance of early onset thrombocytopaenia in alemtuzumab-treated RRMS. Methods A total of 26 patients with RRMS were include...

Journal: :E3S web of conferences 2023

This article discusses the technology of melting high-strength cast iron with a spheroidal graphite shape intended for D-49 type cylinder lid by modifying magnesium (Mg) in ladle and gating systems. Today, it is very important Republic Uzbekistan CIS countries to create improve production prepare high-responsibility parts railway transport. Improvement mechanical operational properties high str...

2013
Francis Barbosa Ferreira Mário Sérgio Rocha Gomes Dayane Lorena Naves de Souza Sarah Natalie Cirilo Gimenes Letícia Eulalio Castanheira Márcia Helena Borges Renata Santos Rodrigues Kelly Aparecida Geraldo Yoneyama Maria Inês Homsi Brandeburgo Veridiana M. Rodrigues

In this work, we describe the molecular cloning and pharmacological properties of an acidic phospholipase A(2) (PLA(2)) isolated from Bothrops pauloensis snake venom. This enzyme, denominated BpPLA(2)-TXI, was purified by four chromatographic steps and represents 2.4% of the total snake venom protein content. BpPLA(2)-TXI is a monomeric protein with a molecular mass of 13.6 kDa, as demonstrated...

Journal: :The FEBS journal 2005
Ying-Ming Wang Hao-Fan Peng Inn-Ho Tsai

To explore the venom diversity of Asian pit vipers, we investigated the structure and function of venom phospholipase A2 (PLA2) derived from two primitive tree vipers Trimeresurus puniceus and Trimeresurus borneensis. We purified six novel PLA2s from T. puniceus venom and another three from T. borneensis venom. All cDNAs encoding these PLA2s except one were cloned, and the molecular masses and ...

Journal: :Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2010
F H R Fagundes M Oliveira S Huancahuire-Vega F F Romero-Vargas L A Ponce-Soto S Marangoni

To illustrate the construction of precursor complementary DNAs, we isolated mRNAs from whole venom samples. After reverse transcription polymerase chain reaction (RT-PCR), we amplified the cDNA coding for a neurotoxic protein, phospholipase A2 D49 (PLA2 D49), from the venom of Crotalus durissus collilineatus (Cdc PLA2). The cDNA encoding Cdc PLA2 from whole venom was sequenced. The deduced amin...

Journal: :Biochimica et biophysica acta 2015
Narine A Ghazaryan Lusine Ghulikyan Arsen Kishmiryan Tatyana V Andreeva Yuri N Utkin Victor I Tsetlin Bruno Lomonte Naira M Ayvazyan

We describe the interaction of various phospholipases A2 (PLA2) from snake venoms of the family Viperidae (Macrovipera lebetina obtusa, Vipera ursinii renardi, Bothrops asper) with giant unilamellar vesicles (GUVs) composed of natural brain phospholipids mixture, visualized through fluorescence microscopy. The membrane fluorescent probes 8-anilino-1-naphthalenesulfonicacid (ANS), LAUDRAN and PR...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید