abstract background: menopause is associated with various complications such as depression, sleep disorders, and genitourinary atrophy. vaginal atrophy occurs due to the loss of steroid hormones, and its major symptoms include vaginal dryness, itching, dyspareunia, and bleeding after intercourse. according to the literature, vitamin e plays a key role in estrogen stability. the aim of this stud...

background & aim:  menopause is one of the most critical stages in a woman’s life. special attention needs to be paid to the quality of life of menopausal women. symptoms of genitourinary atrophy can affect women’s comfort and quality of life. the aim of this study was to compare two treatment methods of vitamin e suppository and conjugated estrogens vaginal cream on the quality of life of meno...

abstract background hemorrhagic cystitis(hc)is one of the most challenging complications in hematopoietic stem cell transplantation(hsct). estrogen is one of the suggested treatments for controllingthis problem. material and methods we performed a randomizedcase - controlled study to evaluate the efficacy of oral conjugated estrogen on hc management in 56hsct patients.patients were randomly ass...

CONTEXT Clinical trial evidence indicates that estrogen therapy with or without progestins increases venous thrombotic risk. The findings from these trials, which used oral conjugated equine estrogens, may not be generalizable to other estrogen compounds. OBJECTIVE To compare risk of venous thrombosis among esterified estrogen users, conjugated equine estrogen users, and nonusers. DESIGN, S...

background: considering the effect of preterm delivery in morbidity and mortality of newborns, its precaution and prevention is so important. objective: to investigate the association between second trimester maternal serum biomarkers (human chorionic gonadotropin, alpha-fetoprotein, non-conjugated estrogen, inhibin a) and pre-term delivery. materials and methods: this is a historical cohort st...

to evaluate the tolerance and effectiveness of conjugated estrogen for women with established post-menopausal osteoporosis and hot flushes, with the use of paired comparison, randomized, we tested during an 10 month period the bone mineral contents and plasma glucose in subjects who afforded by premarin in dosages of 0.625 mg for days 1 to 25 and oral medroxy progesterone acetate for days 15 to...

in a double blind, parallel-group, clinical trial we compared the effects of conjugated estrogen with estrogen plus methyltestosterone in surgically menopausal women. in this study, 251 women were randomly assigned to one of the two regimens: 1-conjugated estrogen 0.625 mg/day +placebo. 2-conjungated estrogen 0.625 mg/day+methyltestosterone 1.25 mg/day (e+a group). study parameters were psychol...

A collection of STEPS published in AFP is available at http://www.aafp.org/ afp/steps. Conjugated estrogens/bazedoxifene (Duavee) combines conjugated estrogen with bazedoxifene, a selective estrogen receptor modulator. Bazedoxifene stimulates estrogen receptors in bone and has antagonistic effects in the breast and uterus.1 Conjugated estrogens/bazedoxifene is labeled for the treatment of moder...

abstract  introduction: during extrinsic coagulation pathway, a complex is developed between factor vii, calcium and tissue factor (a cell membrane lipoprotein that is exposed after cell injury). factor vii needs calcium and vitamin k for its biologic activation. coronary artery disease (cad) can be induced by increased level and activity of the coagulation factors vii, viii and ix. in postmeno...