introduction: functional constipation is one of the most common gastrointestinal symptoms which could affect patients’ quality of life. the colonic transit time test could be used for determining functional constipation subtypes. the aim of our study was to determine the abnormalities of the subtypes of functional constipation using ctt. methods and materials: this cross-sectional study was per...

conclusions it was shown that combination of pectin and eudragits can relatively control drug release in the upper gi. on the other hand, pectin degraded in the presence of pectinase and formulations were susceptible to the colonic media. results it was shown that in the presence of pectin, formulations without erl had a relative resistance to drug release in sgf. pellets containing pectin and ...

background: to compare the efficacy of metronidazole versus placebo in the control of gaseous symptoms inpatients with functional bowel disease. materials and methods: in the absence of organic or systemic diseases, all cases with chief complaints of bloating and normal laboratory tests were consecutively enrolled in this double-blind study. lactase deficiency and bacterial overgrowth were rule...

background geographic information system (gis) software has been used in health care systems to display and analyze spatial pattern of diseases and health services. objectives this study was performed to assess spatial patterns of colon’s pathologic lesions based on the pathologic reports and assess whether it is possible to use gis software in health services. patients and methods archives of ...

AIM To determine the pathogenesis and potential single nucleotide polymorphisms (SNPs) as screening sites for colonic polyps, colon cancer and ulcerative colitis, and to analyze the possible association between these genetic polymorphisms and the three diseases. METHODS We evaluated genetic polymorphisms in 144 newly diagnosed colonic polyp patients, 96 colon cancer patients and 44 ulcerative...