background: potassium citrate (k‑cit) is one of the medications widely used in patients with urolithiasis. however, in some cases with calcium oxalate (caox) urolithiasis, the significant response to alkaline therapy with k‑cit alone does not occur. there is scarce published data on the effect of magnesium chloride (mg‑cl2) on urolithiasis in pediatric patients. this study aimed to evaluate the...

BACKGROUND Antibodies against citrullinated proteins (ACPA) are common in patients with rheumatoid arthritis (RA). ACPA can appear before disease onset and target many self-antigens. Citrullinated fibrin/fibrinogen represents a classical ACPA target antigen, and mass spectrometry of RA synovial fluid reveals elevated citrullinated (cit) fibrinogen (Fib) peptides compared to non-RA controls. We ...

We believe that we can exploit the benefits of combinatorial interaction testing (CIT) on many “non-traditional” combinatorial spaces using many “non-traditional” coverage criteria. However, this requires truly flexible CIT approaches. To this end, we introduce Unified Combinatorial Interaction Testing (U-CIT), which enables practitioners to define their own combinatorial spaces and coverage cr...

In a long-term evolution experiment with Escherichia coli, bacteria in one of twelve populations evolved the ability to consume citrate, a previously unexploited resource in a glucose-limited medium. This innovation led to the frequency-dependent coexistence of citrate-consuming (Cit+) and non-consuming (Cit-) ecotypes, with Cit-bacteria persisting on the exogenously supplied glucose as well as...

Citreoviridin (CIT) is a mycotoxin derived from fungal species in moldy cereals. In our previous study, we reported that CIT stimulated autophagosome formation in human liver HepG2 cells. Here, we aimed to explore the relationship of autophagy with lysosomal membrane permeabilization and apoptosis in CIT-treated cells. Our data showed that CIT increased the expression of LC3-II, an autophagosom...

Different IS research methods focus on or measure different aspects of IS phenomena, and studies based on various methodologies thus contribute to the accumulation of strong evidence to support IS theories. We conducted a systematic and reproducible review of ten years of Critical Incident Technique (“CIT”) papers published in the IS Scholars Basket of eight journals. CIT is used extensively in...