100 patients with beta-thalassemia trait, comprised of 55 men and 45 women, participated in a study to measure serum lipoproteins. the results were compared with the data obtained from 100 control subjects of the same age and sex. a significantly lower level of mean serum total cholesterol and ldl cholesterol, and a much higher level of hdl cholesterol were obtained in beta-thalassemia trait as...

Hemolysis presents as acute or chronic anemia, reticulocytosis, or jaundice. The diagnosis is established by reticulocytosis, increased unconjugated bilirubin and lactate dehydrogenase, decreased haptoglobin, and peripheral blood smear findings. Premature destruction of erythrocytes occurs intravascularly or extravascularly. The etiologies of hemolysis often are categorized as acquired or hered...

Sixty-two patients were investigated for chronic intravascular hemolysis from 3 months to 6iS years following aortic valve replacement; 27 patients had Starr-Edwards prostheses and 35 fascia lata grafts. The findings are suggestive of a significantly higher incidence and degree of hemolysis in patients with Starr-Edwards prostheses compared to those with fascia lata grafts. In both groups regur...

Two cases of hemolytic anemia with spherocy­tosis were investigated. lnspite of chronic hemolysis tl::crc was no radiological changes in flat bones. Ma­nagement and entity of spherocytosis is discussed m detail in this paper. 

Several hemolytic markers are available to guide the differential diagnosis and to monitor treatment of hemolytic conditions. They include increased reticulocytes, an indicator of marrow compensatory response, elevated lactate dehydrogenase, a marker of intravascular hemolysis, reduced haptoglobin, and unconjugated hyperbilirubinemia. The direct antiglobulin test is the cornerstone of autoimmun...

The incidence and severity of chronic intravascular hemolysis was evaluated in a total of 41 patients following mitral valve replacement. Valve replacement was with a gamma-radiated frame-mounted aortic homograft in 21 patients and with a composite seat Starr-Edwards prosthesis, model 6310 or 6320, in 20 patients. The parameters used to assess hemolysis were hemoglobin, hematocrit, reticulocyte...