DOI: 10.21276/sjams.2017.5.9.49 Abstract: Evolvulus alsinoides Linn. Is a medicinal plant that belongs to the family convolvulaceae. This study seeks to evaluate the effects of the aqueous extract of Evolvulus alsinoides Linn. on sperm parameters and the testis. A total of fifty (50) Wistar albino rats weighing 135-150g were used in this research. The rats were divided into five (I-V) Groups of...

Nephrotoxicity remains a common untoward effect of cisplatin therapy with limited effective chemopreventive options available till date. This study aims to evaluate the possible chemopreventive effect and mechanism(s) of action of 2 mgkg-1 and 5 mgkg-1 of Tadalafil in cisplatin-induced nephrotoxic rats. In this study, twenty-five male Wistar rats were randomly divided into five groups (n = 5 ra...

Lead (Pb) is the most ancient poison known to man. In the present study, amount of accumulation of Pb in liver, kidney, ovary and testes of rain quail was studied using different doses of lead. Spectrophotometric analysis of heavy metal treated organs was carried out to determine the amount of metal accumulation in these organs. LD50 value was 4 ppm. Dose of lead was given in three ranges of lo...

1. The effects of chlorpromazine on sympathetic neuroeffector transmission have been studied in the rabbit isolated pulmonary artery and aorta. 2. Chlorpromazine (10(-8)-10(-5) M), prazosin (10(-9)-10(-7) M) and phentolamine (3 x 10(-8)-3 x 10(-5) M) decreased the contractions of pulmonary artery evoked by electrical field stimulation (150 pulses; 3 Hz). The rank order of inhibitory potency (ID...

Chronic pain is a common complication of diabetes. The aim of the present study was to characterise pain behaviour in a high fat diet/streptozotocin (HFD/STZ) model of diabetes in the rat, investigate spinal mechanisms, and determine the effects of antidiabetic interventions. Three-week consumption of a high fat diet followed by single injection of STZ (45 mgkg(-1)) produced sustained changes i...

synthetic lhrha or its superactive analogues stimulate gth release. it shows an overlap in the biological activity of lhrha and gnrh in many teleost species. the aim of the present study was to investigate the effects of lhrha2, metoclopramide and chlorpromazine on hpg axis and plasma levels of ght ii. luteinizing hormone releasing hormone analogue 2 (lhrha2) (3 mg/kg) with dopamine antagonis’s...

The metamorphic response of pediveliger larvae of Mytilus galloprovincialis to the neurotransmitter blockers chlorpromazine, amitriptyline, rauwolscine, idazoxan, atenolol and butoxamine, and to tetraethylammonium chloride (TEA) was investigated through a series of bioassays. Chlorpromazine, amitriptyline and idazoxin inhibited larval metamorphosis induced by 10⁻⁴ M epinephrine. The concentrati...

Two ectomycorrhizal macrofungal Amanita species of the section Lepidella, A. strobiliformis and A. solitaria, were found to hyperaccumulate silver (Ag). All samples were collected from non-argentiferous areas with background Ag content in soils (0.07-1.01 mgkg(-1) Ag). The Ag contents of both Amanita species were mostly in the range of 200-700 mgkg(-1)D.W. with the highest Ag content of 1253 mg...

The immunomodulatory function of longan pulp polysaccharide-protein complex (LP3) was investigated in immunosuppressed mice models. Compared with the model control, peroral administration of 100 mgkg⁻¹d⁻¹ LP3 could significantly increase/enhance antibody production against chicken red blood cell (CRBC), concanavalin A (ConA)-induced splenocyte proliferation, macrophage phagocytosis, NK cell cyt...