background and objective: febrile convulsions (fc) are the most common seizure disorders in children. lumbar puncture should be considered in any case with fc who is suspected to intracranial infections. this study determined white blood cell and polymorphonuclear cell counts, protein and glucose levels in cerebrospinal fluids (cfs) of children that were hospitalized with fc. methods: in this c...

background and objective: febrile convulsions (fc) are the most common seizure disorder in children. lumbar puncture should be considered in any case with fc who is suspected to intracranial infections. this study determined white blood cell and polymorphonuclear cell counts, and protein and glucose levels in cere-brospinal fluids (cfs) of children hospitalized with fc. methods: in this cross s...

BACKGROUND Chronic Fatigue Syndrome (CFS), Persian Gulf War Illness (PGI), and fibromyalgia are overlapping symptom complexes without objective markers or known pathophysiology. Neurological dysfunction is common. We assessed cerebrospinal fluid to find proteins that were differentially expressed in this CFS-spectrum of illnesses compared to control subjects. METHODS Cerebrospinal fluid speci...

Background Chronic fatigue syndrome (CFS) and fibromyalgia (FM) frequently have overlapping symptoms, leading to the suggestion that the same disease processes may underpin the two disorders - the unitary hypothesis. However, studies investigating the two disorders have reported substantial clinical and/or biological differences between them, suggesting distinct pathophysiological underpinnings...

BACKGROUND Extracellular RNAs (exRNAs) in human body fluids are emerging as effective biomarkers for detection of diseases. Saliva, as the most accessible and noninvasive body fluid, has been shown to harbor exRNA biomarkers for several human diseases. However, the entire spectrum of exRNA from saliva has not been fully characterized. METHODS Using high-throughput RNA sequencing (RNA-Seq), we...

OBJECTIVES Previous research has provided evidence for dysregulation in peripheral cytokines in patients with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME). To date only one study has examined cytokines in cerebrospinal fluid (CSF) samples of CFS/ME patients. The purpose of this pilot study was to examine the role of cytokines in CSF of CFS/ME patients. METHODS CSF was collected...

MRI has previously provided conflicting results when used to search for brain abnormalities in sufferers of chronic fatigue syndrome (CFS). Eighteen CFS patients and nine healthy volunteers each underwent MRI on two occasions, one year apart. The resulting images were examined for abnormalities in brain atrophy, deep white matter hyperintensities (WMH) and cerebral blood and cerebrospinal fluid...

BACKGROUND Neurologic Post Treatment Lyme disease (nPTLS) and Chronic Fatigue (CFS) are syndromes of unknown etiology. They share features of fatigue and cognitive dysfunction, making it difficult to differentiate them. Unresolved is whether nPTLS is a subset of CFS. METHODS AND PRINCIPAL FINDINGS Pooled cerebrospinal fluid (CSF) samples from nPTLS patients, CFS patients, and healthy voluntee...

treatment of hydrocephalus in posterior fossa tumors in children is still a matter of controversy and different centers have their own routines. in this regard, hospital records of all children with posterior fossa tumors treated in our center during the interval of 1985-1995 were reviewed. patients’ demographic and diagnostic data were analyzed and the frequencies of shunting procedures were d...

enterobius vermicularis is a nematod of large intestine in man. extra intestinal localization of this parasite is rare. a 60 year old man was admitted to the hospital with the clinical manifestation of meningitis. in laboratory examination of cerebrospinal fluid (c.s.f), the appearance was red, albu-min level was high and the glucose showed normal value. haematoxylin and eosin stained slides pr...