نتایج جستجو برای: cell free dna

تعداد نتایج: 2457858  

Journal: :آزمایشگاه و تشخیص 0
محمد علی تخشید mohammad ali takhshid diagnostic laboratory sciences and technology research center, school of paramedical sciences, shiraz university of medical sciences, shiraz, iranگروه علوم آزمایشگاهی، دانشکده پیراپزشکی، دانشگاه علوم پزشکی شیراز مرضیه علیزاده marzieh alizadeh diagnostic laboratory sciences and technology research center, school of paramedical sciences, shiraz university of medical sciences, shiraz, iranمرکز تحقیقات علوم و فن آوری تشخیص آزمایشگاهی ،گروه علوم آزمایشگاهی، دانشکده پیراپزشکی، دانشگاه علوم پزشکی شیراز

cell free dnas (cfdnas) are small fragments of genomic or mitochondrial dna releasing from cells into the blood stream. the presence of cfdna in the human circulatory system has been shown for the first time in 1948 however, the potential clinical applications of cfdna remained unknown until recent progress in detection and quantification of these molecules by sensitive methods. in this paper, ...

Journal: :journal of comprehensive pediatrics 0
mahsa motavaf department of genetics, tarbiat modares university, tehran, ir iran majid sadeghizadeh department of genetics, tarbiat modares university, tehran, ir iran; department of genetics, faculty of biological sciences, tarbiat modares university, p. o. box: 14115-175, tehran, ir iran. tel: +98-2182884409, fax: +98-2182883463سازمان اصلی تایید شده: دانشگاه تربیت مدرس (tarbiat modares university)

context prenatal testing aims to identify fetal chromosomal and genetic disorders prior to delivery. current invasive procedures such as amniocentesis and chorionic villus sampling (cvs) pose a risk to mother and fetus and such diagnostic procedures are available only to high-risk pregnancies, which limits aneuploidy detection rate. the identification of cell-free fetal dna (cffdna) in maternal ...

تخشید, محمد علی, علیزاده, مرضیه,

به انواع مختلف اسیدهای نوکلئیک آزاد در پلاسما شامل قطعات DNA ژنومی،DNA میتوکندریایی، DNA و mRNA های ویروسی و همچنین انواع miRNA اصطلاحا Cell–free nucleic acid گفته می شود. بخش مهمی از این اسیدهای نوکلئیک آزاد در پلاسما را Cell–free DNA (cfDNA) تشکیل می دهد. cfDNA به صورت قطعاتی با وزن مولکولی حدود KB 21-0.18 در سرم یا پلاسمای افراد سالم و افراد مبتلا به بسیاری از بیماری ها قابل تشخیص هستند. ...

Journal: :avicenna journal of medical biotechnology 0

cell free dna (cfdna) is a genetic biomarker that is present in serum or plasma in high concentration in many types of cancer. identification of circu-lating cancer related dna molecules in serum or plasma is a non-invasive tool for early diagnosis and prognosis in many cancer patients. for this review, study selection and data extraction were performed by the authors. detection of point mutati...

Journal: :acta medica iranica 0
hamid reza khorram khorshid genetic research centre, university of social welfare and rehabilitation sciences, tehran, iran. maryam zargari biology department, science and research branch, islamic azad university (iau), tehran, iran. and reproductive biotechnology research centre, avicenna research institute (acecr), tehran, iran. mohammad reza sadeghi reproductive endocrinology and andrology research centre, avicenna research institute (acecr), tehran, iran. haleh edallatkhah reproductive biotechnology research centre, avicenna research institute (acecr), tehran, iran. mohammad hassan shahhosseiny microbiology department, shahr-e-qods branch, islamic azad university (iau), tehran, iran. koorosh kamali reproductive biotechnology research centre, avicenna research institute (acecr), tehran, iran.

nowadays, new advances in the use of cell free fetal dna (cffdna) in maternal plasma of pregnant women has provided the possibility of applying cffdna in prenatal diagnosis as a non-invasive method. in contrary to the risks of invasive methods that affect both mother and fetus, applying cffdna is proven to be highly effective with lower risk. one of the applications of prenatal diagnosis is fet...

Kakal F Khan Y Mohammed N, QureshR Shiekh L Somani M Zafar W

Background: Current prenatal diagnosis requires invasive testing which carries a 1-4% procedure-related-risk of miscarriage; hence, non-invasive techniques are desired. The recent demonstration of cell-free-fetal-DNA enriched from maternal plasma has opened new possibilities for non-invasive-prenatal-diagnosis of not only genetic-disorders such as β-thalassaemia and haemophilia but also chromos...

Kakal F Khan Y Mohammed N, Qureshi Shiekh L Somani M Zafar W

Background: Current prenatal diagnosis requires invasive testing which carries a 1-4% procedure-related-risk of miscarriage; hence, non-invasive techniques are desired. The recent demonstration of cell-free-fetal-DNA enriched from maternal plasma has opened new possibilities for non-invasive-prenatal-diagnosis of not only genetic-disorders such as β-thalassaemia and haemophilia but also chromos...

Journal: :International Journal of Health Science 2023

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه شهرکرد - دانشکده دامپزشکی 1392

هم سلول¬های کامل جنینی و هم نوکلئیک اسیدهای آزاد سلول¬های جنینی(cell-free fetal nucleic acids(cffdna)) در طول دوران آبستنی از جفت عبور می¬کند و در جریان خون مادری در گردش می باشند. در مطالعه اخیر ما یک روش جدید، با استفاده از ژن آمیلوژنین (amelogenin) برای تعیین جنسیت جنین در گوسفند را مورد بررسی قرار دادیم. و با استفاده از تکنیک real time pcr (rt-qpcr) quantitative میزان dna جنینی در جریان خون...

Journal: :Obstetrical & Gynecological Survey 2016

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