Beale SC (1998) Capillary electrophoresis. Analytical Chemistry 70: 279. (This journal prints every two years a review on capillary electrophoresis. The article is written by an expert in the Reld and covers more or less all developments in CE including CGE of the preceding years.) Grossmann PD and Colburn JC (eds) (1996) Capillary Electrophoresis: Theory and Practice. San Diego: Academic Press...

Despite the significant advantages of capillary isoelectric focusing over gel isoelectric focusing, widespread acceptance of the technique as a replacement for gel isoelectric focusing has not occurred. Several factors contribute to capillary isoelectric focusing’s slower-than-expected adoption; perhaps the most important are the performance and procedural difficulties introduced when capillary...

he number of biotechnology products on the market and, particularly, in development has increased enormously during the past decade. Biological products generally are more complex than their small-molecule counterparts. Some product variants — such as deamidated, clipped, aggregated, or misfolded species — could be present in the process stream and even in the final products. Regulatory agencie...

Capillary zone electrophoresis and carrier ampholytes based capillary electrophoresis have been used as a second separation step to Off-Gel isoelectric focusing for the analysis of complex peptide mixtures. A tryptic digest of four proteins (bovine serum albumin, beta-lactoglobulin, horse myoglobin, cytochrome c) has been chosen as a peptide test mixture. After assessment of different modes of ...

a total of 781 serum and 827 red cell samples from four populations of iran (kashan, ardestan, asrara and ardabil) were sub-typed by isoelectric focusing for group-specific componet and red cell enzyme phosphoglucomutase, locus one, respectively. heterogeneity test revealed no significant differences among the populations studied regarding both pgm1 and gc systems.