Coccidioidomycosis is a common cause of community-acquired pneumonia (CAP) in disease-endemic areas. Because testing rates influence interpretation of reportable-disease data and quality of CAP patient care, we determined the proportion of CAP patients who were tested for Coccidioides spp., identified testing predictors, and determined the proportion of tested patients who had positive coccidio...

BACKGROUND The credibility of prognostic indicators in nursing-home-acquired pneumonia (NHAP) is not clear. We previously reported a simple prognostic indicator in community-acquired pneumonia (CAP): blood urea nitrogen to serum albumin (B/A) ratio. This retrospective study investigated the prognostic value of severity indicators in NHAP versus CAP in elderly patients. METHODS Patients aged ≥...

Transcription activation by Escherichia coli catabolite activator protein (CAP) at each of two classes of simple CAP-dependent promoters is understood in structural and mechanistic detail. At class I CAP-dependent promoters, CAP activates transcription from a DNA site located upstream of the DNA site for RNA polymerase holoenzyme (RNAP); at these promoters, transcription activation involves pro...

Class II CAP-dependent promoters, interacting with the RNAP ␣ subunit C-terminal domain (␣CTD) and facilitat-At Class I CAP-dependent promoters, interaction between the activating region and ␣CTD (and concomitant St. Louis, Missouri 63104 recruitment of RNAP to promoter DNA) appears to be the entire basis of transcription activation. Thus, at Class Summary I CAP-dependent promoters, removal of ...

STUDY OBJECTIVE To determine the extent of intravenous (IV) antibiotic use for community-acquired pneumonia (CAP) in emergency departments, the practice patterns in seven emergency departments serving the adult residents of one Canadian city were observed. METHODS An observational study of nonhospitalized adults diagnosed with CAP in seven emergency departments was conducted between November ...

CONTEXT There are up to 1 million patients treated in acute-care hospitals for community-acquired pneumonia (CAP), with an estimated annual cost > 8 billion dollars. A newly validated CAP outcomes prediction rule developed by Fine and colleagues has been advocated as a guide to hospitalization decisions. OBJECTIVE To evaluate the clinical characteristics, costs of care, and resource utilizati...

IN THE PERPETUALLY RESOURCE-STARVED environment of public health, where each disease or risk factor has to fight for a scrap of the federal budget, it is easy to forget how fast progress can be made when appropriate policy attention and resources are marshaled to solve a problem. The natural response of public health professionals to the starvation diet is to maintain low expectations. But thos...

OBJECTIVE Report the relationship of composition with age and sex of the patients. MATERIAL AND METHOD A series of 426 urinary stones, 33 from the lower (LUT) and 393 from the upper urinary tract (UUT) of adults, were analyzed for their chemical composition using infrared spectroscopy. The majority of LUT stones were from males (n = 26) and in the age group beyond 60 years (n = 20). RESULTS...