the effect of melatonin and bromocryptine on body weight, fibre shedding and cashmere traits was investigated by using 24 raeini female goats (2-3 years old) in four experimental groups: control (c); melatonin (mi) implant (18 mg at first and repeated after 40 days), bromocryptine (b) injection, (0.5 mg/kg bw per three days) melatonin and bromocryptine implant and injection (mib). all goats wer...

An experiment was carried out on 10 advance pregnant Murrah buffaloes to determine the role of hormones in milk secretion around parturition. Experimental animals were administered with a single injection of bromocryptine, @ 100 μg/kg BW, for 5 days before expected calving, whereas control group buffaloes were injected with placebo injections. Blood samples collected before parturition (-5,-4,-...

To determine the effect of bromocryptine on plasma prolactin, metabolites and milk production, six healthy crossbred goats in their second or third lactation were selected from the institute's goat herd. The goats were injected with bromocryptine @ 5 mg per day intramuscularly for a period of 5 days during 55±60 days of lactation (period I) and treatment was repeated after 14 days for an additi...

The purpose of this study was to determine the early role of estrogen and prolactin on subsequent hormone dependency of carcinogen-induced mammary tumors. Virgin 57-day-old Sprague-Dawley rats were given i.v. injections of 7,12-dimethylbenz(a)anthracene (DMBA). One day prior to and 7 days after DMBA administration, the rats were divided into separate groups and given: a daily 0.1-ml s.c. inject...

The purpose of this study was to determine the early role of estrogen and prolactin on subsequent hormone dependency of carcinogen-induced mammary tumors. Virgin 57-day-old Sprague-Dawley rats were given i.v. injections of 7,12-dimethylbenz(a)anthracene(DMBA). One day prior to and 7 days after DMBA administration, the rats were divided into separate groups and given: a daily 0.1-ml s.c. injecti...

To test whether growth of the winter coat in short day lengths is contingent on suppression of plasma prolactin (Prl) levels, female meadow voles (Microtus pennsylvanicus) were kept in short day lengths for 12 weeks and were injected daily with saline or Prl; long-day animals were treated with either the dopamine agonist, bromocryptine (bromo), bromo plus Prl, or saline. Prl treatment prevented...

Bromocryptine, a dopamine agonist, effectively inhibited the black-adaptation of prometamorphic tadpoles of the bullfrog Rana catesbeiana. The melanophore index (MI) of bromocryptine-injected tadpoles was significantly lower than that of controls. Bromocryptine was also effective in lightening the skin color of the hypophysectomized tadpoles bearing a pituitary graft. When pimozide, a dopamine ...

This study examined the influence of high dietary fat intake on the development of ovarian-independent mammary tumors in both vehicle-treated controls and rats made deficient in estrogen and prolactin during tumor induction. The majority of 7,12-dimethylbenz(a) anthracene (DMBA)-induced mammary tumors in rats are dependent on estrogen and prolactin for growth, and suppression of prolactin and e...

This study examined the influence of high dietary fat intake on the development of ovarian-independent mammary tumors in both vehicle-treated controls and rats made deficient in estrogen and prolactin during tumor induction. The majority of 7,12dimethylbenz(a)anthracene(DMBA)-induced mammary tumors in rats are dependent on estrogen and prolactin for growth, and suppression of prolactin and estr...