this study a novel high performance liquid chromatography for the assay of nystatin in oral and vaginal tablets were optimized and validated using box–behnken experimental design. the method was performed in the isocratic mode on a rp-18 column (30 °c) using a mobile phase consisting of 0.05 m ammonium acetate buffer/ methanol mixture (30:70) and a flow-rate of 1.0 ml/min. the method was valida...

fruit waste extract was selected as the sole substrate for carotenoid production and the effect of parameters like ph, temperature and agitation have been studied. a two-step simple sequential strategy was employed for the optimization of carotenoid production by rhodotorula rubra. in the first step, one factor at a time was employed to evaluate the impact of ph on carotenoid production. the ou...

the current investigation presents the role of gooseberry (phyllanthus acidus) seeds as an effective biosorbent for remediating chromium (vi)), a toxic heavy metal pollutant commonly found in effluents from tanneries and relevant industries. biosorption was affected by ph, temperature and initial metal concentration. furthermore, there is a need to understand the holistic effect of all variable...

for all industrial processes, modelling, optimisation and control are the keys to enhance productivity and ensure product quality. in the current study, the optimization of process parameters for improving the conversion of isoeugenol to vanillin by psychrobacter sp. csw4 was investigated by means of taguchi approach and box-behnken statistical design under resting cell conditions. taguchi desi...

For all industrial processes, modelling, optimisation and control are the keys to enhance productivity and ensure product quality. In the current study, the optimization of process parameters for improving the conversion of isoeugenol to vanillin by Psychrobacter sp. CSW4 was investigated by means of Taguchi approach and Box-Behnken statistical design under resting cell conditions. Taguchi desi...

For all industrial processes, modelling, optimisation and control are the keys to enhance productivity and ensure product quality. In the current study, the optimization of process parameters for improving the conversion of isoeugenol to vanillin by Psychrobacter sp. CSW4 was investigated by means of Taguchi approach and Box-Behnken statistical design under resting cell conditions. Taguchi desi...

in this study, the influence of the salts as an additive on the performance of the membrane was investigated and an extensive work was performed to optimize pvdf hollow fiber membranes through a response surface methodology (rsm). the prepared membranes were characterized by sem, contact angle and lep measurement. then, the rsm was used for the optimization of surface pore size, porosity and hy...

Box and Behnken (1960) constructed 10 three-level, second-order designs, while their 1958 technical report contained seven additional designs. This series of designs is based on combining 2 or 2 designs in different subsets of the t factors, with k < t. The subsets of size k were determined using balanced (or partially balanced) incomplete block designs. This present article offers additional B...

Response surface methodology was engaged for the optimization of diverse nutritional and physical parameters for laccase production by Streptomyces chartreusis strain NBRC 12753 in the submerged fermentation process. Screening of production parameters was executed using Plackett–Burman design and the variables with statistically momentous effects on laccase production were recognized. Variables...