Viewer/Itinerary Planner. Society for Neuroscience. Washington, DC, USA. http://sfn.scholarone.com. 44. Zhang, Z.G., et al. 2000. VEGF enhances angiogenesis and promotes bloodbrain barrier leakage in the ischemic brain. J. Clin. Invest. 106:829–838.

It is known that circumventricular organs that are located around the ventricular system of the brain are lack of blood-brain barrier and support the body water-salt balance. They also effect many physiological events such as some neuroendocrine and reproduction mechanisms. In different pathological conditions their results and the step in which the circumventricular organs are affected are unk...

We present the review of clinical and experimental studies on pathogenesis neurorheumatological complications (NRC) in COVID-19. The influence systemic hyperinflammation caused by impaired innate immunity functioning neurovascular endothelium bloodbrain barrier, activation signaling pathways parainfectious autoimmunity central nervous system were analyzed. Hyperinflammation has been shown to co...

Increased permeability or " breakdown " of the bloodbrain barrier following the carotid injection of various contrast media has been previously documented [1 -6]. Trans ient opening of the blood-brain barrier may also be produced by injecting hyperosmotic mannitol or arabinose into th e interna l carotid artery [7 -12]. CT scanning has recently been appli ed to the definition and quantitation o...

The effect of pretreatment with the calcium antagonist nimodipine on the pathophysiological events which follow an intracerebral haemorrhage in rats was compared with a similar control group. Cerebral blood flow was higher and the amount of pathologically determined ischaemic damage measured by light microscopy was less in the nimodipine pretreated group. Bloodbrain barrier permeability was inc...

Background Multiple sclerosis (MS) is an autoimmune disease of central nervous system, which unknown etiology, but recent studies suggest important role of oxidative stress in its pathogenesis. The aim of our study was to analyze various markers of oxidative and nitrative damage, their mutual correlations and correlations with the state of the bloodbrain barrier (BBB) in multiple sclerosis pati...

Disruption of the blood brain barrier plays a significant role in the pathophysiology of subarachnoid haemorrhage. Experimental studies concerning subarachnoid haemorrhage suggested the primary role of free radicals and subsequently lipid peroxidation in the pathogenesis of vasospasm. In this experimental study the role of deferoxamine on blood brain barrier disturbance in vasospasm was evaluat...