نتایج جستجو برای: benzo (a) pyrene

تعداد نتایج: 13434332  

ژورنال: طب کار 2015
آقائی, حامد, اعظم, کمال, امیدی, فریبرز, رسالتی, شهره, شاهطاهری, جمال الدین, عارفیان, صفورا, کاکویی, حسین,

Background: Asphalt workers are exposed to dangerous agents in his workplace that might result in occupational diseases. Benzo (a) pyrene as a human carcinogen, is emission from hot asphalt and asphalt workers are exposed with it. The aim of this study was, evaluation of respiratory exposure to benzo (a) pyrene among asphalt workers. Method: In this study, 42 samples were collected from breath...

Journal: :the iranian journal of pharmaceutical research 0
samira eslamizad department of pharmacology and toxicology, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran yazdanpanah hassan yazdanpanah department of pharmacology and toxicology, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran katayoun javidnia medicinal and natural products chemistry research centre, shiraz university of medical sciences, shiraz, iran ramezan sadeghi department of pharmacology and toxicology, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran mitra bayat phytochemistry research center, shahid beheshti university of medical sciences, tehran, iran. sara shahanipour medicinal and natural products chemistry research centre, shiraz university of medical sciences, shiraz, iran

a fast and simple modified quechers (quick, easy, cheap, rugged and safe) extraction method based on spiked calibration curves and direct sample introduction was developed for determination of benzo[a]pyrene (bap) in bread by gas chromatography-mass spectrometry single quadrupole selected ion monitoring (gc/ms-sq-sim). sample preparation includes extraction of bap into acetone followed by clean...

Journal: :طب کار 0
حسین کاکویی h kakoei [email protected] حامد آقائی h aghaei [email protected] جمال الدین شاهطاهری j shahtaheri علوم پزشکی تهران فریبرز امیدی f omidi علوم پزشکی تهران صفورا عارفیان s arefian علوم پزشکی تهران کمال اعظم k azam علوم پزشکی تهران شهره رسالتی

background: asphalt workers are exposed to dangerous agents in his workplace that might result in occupational diseases. benzo (a) pyrene as a human carcinogen, is emission from hot asphalt and asphalt workers are exposed with it. the aim of this study was, evaluation of respiratory exposure to benzo (a) pyrene among asphalt workers. method: in this study, 42 samples were collected from breathi...

Journal: :Cancer research 1976
J Kapitulnik W Levin H Yagi D M Jerina A H Conney

Seven phenols of benzo(a)pyrene (4-, 5-, 6-, 7-, 8-, 9-, and 10-hydroxybenzo(a)pyrene) were tested for carcinogenicity on mouse skin by application of 0.4 mumole of compound once every two weeks for 56 weeks. None of the seven phenols tested was carcinogenic to mouse skin, while treatment with the same dose of benzo(a)pyrene produced tumors in 92% of the treated animals. The lack of carcinogeni...

Journal: :iranian journal of pharmaceutical research 0
samira eslamizad department of pharmacology and toxicology, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran. farzad kobarfard department of medicinal chemistry, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran and phytochemistry research center, shahid beheshti university of medical sciences, tehran, iran. katayon javidnia medicinal and natural products chemistry research centre, shiraz university of medical sciences, shiraz, iran. ramezan sadeghi department of pharmacology and toxicology, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran. mitra bayat phytochemistry research center, shahid beheshti university of medical sciences, tehran, iran. sara shahanipour medicinal and natural products chemistry research centre, shiraz university of medical sciences, shiraz, iran.

a fast and simple modified quechers extraction method was developed for determination of benzo[a]pyrene (bap) in 137 traditional (sangak), semi-industrial (sangak) and industrial bread samples using spiked calibration curves by gc/ms. sample preparation includes extraction of bap into acetone followed by cleanup with dispersive solid phase extraction. the limit of detection and limit of quantif...

Journal: :international journal of environmental research 2014
f. abdolahpur monikh m. hosseini j. kazemzadeh khoei a.f. ghasemi

in this study, three stations of the north persian gulf were analyzed in order to determinethe effect of trophic levels on the concentration of harmful pahs in fish and sediment. in all cases,similar distributions were observed in which benzo(a)pyrene largely predominated andbenzo(b)fluoranthene and pyrene were the second major compounds in fish tissues. the predominantcomponents of pahs in sed...

Journal: :Drug metabolism and disposition: the biological fate of chemicals 2001
M O James Z Tong L Rowland-Faux C S Venugopal K M Kleinow

The intestinal bioavailability and biotransformation of 3-hydroxybenzo(a)pyrene, a major metabolite of benzo(a)pyrene in many animal species, was investigated in an in situ isolated intestinal preparation from the channel catfish, and in vitro with preparations of catfish intestine and blood. 3-Hydroxybenzo(a)pyrene was a good substrate for adenosine 3'-phosphate 5'-phosphosulfate (PAPS)-sulfot...

2007
Helen P. Shu Edwin N. Bymun

In vitro studies have previously indicated that benzo(a)pyrene distributes primarily into the plasma lipoprotein fraction when incubated with whole plasma. Hydroxylated metabolites of benzo(a)pyrene distribute increasingly into the albumin fraction as the degree of metabolite hydroxylation increases. This report assesses the influence of plasma lipoproteins and albumin as carriers for benzo(a)p...

Journal: :Cancer research 1981
G M Holder B Tierney E Bresnick

The binding of [3H]benzo(a)pyrene to proteins of rat liver cytosol, the nuclear uptake of cytosolic protein-bound [3H]-benzo(a)pyrene, and the subsequent nuclear metabolism of the polycyclic hydrocarbon were investigated. The binding of [3H]benzo(a)pyrene to cytosol had a saturable high affinity component with a Kd of 2.54 nM and a capacity of 530 fmol/mg protein. Specific binding of [3H]benzo(...

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