نتایج جستجو برای: based vaccine.
تعداد نتایج: 3025578 فیلتر نتایج به سال:
introduction: glycoprotein b (gb) is the major antigen for induction of humoral responses against human cytomegalovirus (hcmv) making it an attractive candidate for immune prophylaxis. in the present study, the humoral immune response of balb/c mice to a truncated hcmv gb protein fused with gfp was evaluated. methods: the truncated gb coding sequence was synthesized and cloned in pegfpn1 eukary...
acute myeloid leukemia (aml) is a type of poor prognosis hematological malignancies characterized by heterogeneous clonal expansion of myeloid progenitors. leukemic stem cells are thought to form the majority of a cell population in minimal residual diseases (mrds) which are resistant to current chemotherapeutic regimens and mediate disease relapse. current therapeutic vaccine strategies have d...
سیتومگالو ویروس یکی از شایع ترین ویروس های بیماری زا در سراسر جهان است. در موارد عفونت مادرزادی منجر به اختلالات شدید عصبی و حتی مرگ جنین و در افراد با سرکوب ایمنی باعث بروز علائم بالینی شدیدی می شود. از میان تمامی استراتژی های واکسیناسیون، واکسن های بر پایه اپی توپ های شاخص ایمنی زا (epitope-based vaccine)، بهترین راهکار برای پیشگیری از ابتلا به این ویروس می باشند. در این مطالعه اپی توپ های ش...
Background: Vaccination is preventive behavior, and vaccine literacy and hesitancy appear to influence vaccination. The aim of this study was to determine the role of vaccine literacy and hesitancy on the acceptance of the COVID-19 vaccine. Materials and Methods: In this cross-sectional study, 2185 residents over 18 years old in urban and rural health centers in three cities of Dashtestan, Dash...
هدف اصلی واکسنهای دامی بهبود و کنترل محصولات دامی و کاهش مصرف دارو و هورمون ها می باشد. ویروس بیماری تب برفکی باعث زیان های اقتصادی زیادی در دام ها می شود. مطالعات ایمونولوژیکی در ویروس تب برفکی نشان داده است که اپی توپ غالب مسئول القائ پاسخ آنتی بادی خنثی کننده، باقیمانده های آمینو اسیدی موجود در لوپ g-h هستند که لوپ سطحی پروتئین ساختمانی vp1 می باشد. واکسن رایج این بیماری به دلایلی چون نیمه ...
Background and Objectives: Vaccine acceptance could seriously affect global efforts to control the Covid-19 pandemic. The aim of this study was to estimate the Covid-19 vaccine acceptance and its related factors in Tehran and Kermanshah. Methods: A population-based cross-sectional study was conducted on 850 participants in Tehran and Kermanshah using the random digit dialing method. Multipl...
Background: Due to high genetic variation in human leukocyte antigen )HLA( alleles, epitope-based vaccines don’t show equal efficacy in different human populations. therefore, we proposed a multi-epitope vaccine against SARS-CoV-2 for Iranian populations. Materials and Methods: For this purpose, the proteins without allergenicity and high antigenicity as well as conservancy level from SARS-CoV...
Coagulopathies after vaccination against SARS-CoV-2: The sole solution might lead to another problem
The common reported adverse impacts of COVID-19 vaccination include the injection site’s local reaction followed by various non-specific flu-like symptoms. Nevertheless, uncommon cases of vaccine-induced immune thrombotic thrombocytopenia (VITT) and cerebral venous sinus thrombosis (CVST) following viral vector vaccines (ChAdOx1 nCoV-19 vaccine, Ad26.COV2 vaccine) have been reported. This liter...
Background and Objectives: After the introduction of the pneumococcal vaccine, an increase has been observed in the disease due to nonspecific stereotypes of the vaccine. This study was conducted to determine the spatial distribution of pneumococcal vaccine coverage and common stereotypes of streptococcus pneumonia after vaccine introduction in the vaccine recipient countries. Methods: The ...
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