A sandwich enzymeimmunoassay (EIA) for pregnant mare serum gonadotropin (PMSG) using a microtiter plate was developed. Sensitivity of the assay to PMSG was 15.6 mIU/ml (0.2 ng/well). The PMSG levels in serum were measured with the EIA in superovulated and anti-PMSG rabbit antiserum treated mice and heifers. In mice, the PMSG blood level was measurable in the serum 4-6 days after intraperitoneal...

Social stress may precipitate psychopathological disorders in susceptible individuals. The present experiments were focused on the biology beyond the differential susceptibility to social stress. Social defeat, an ethologically relevant stressor known to elicit different coping strategies, was used in two mouse strains differing for baseline emotionality, such as C57BL6/J and BalbC. In separate...

The interaction of highly purified pregnant mare serum gonadotropin (PMSG or eCG) has been studied in rat and equine testis homogenates. In the rat studies, unlabeled PMSG was shown to possess both high levels of intrinsic follitropin-like and lutropin-like activity when the inhibition of radioiodinated follitropin and lutropin binding by unlabeled PMSG was studied. Radioiodinated PMSG exhibite...

The influence of pregnant mares' serum gonadotropin (PMSG) on reproductive performance of sheep bred by artificial insemination (AI) was studied in the anestrous and estrous seasons. Ewes were treated with progestogenimpregnated intravaginal sponges in June and October. One-half of the ewes in each trial received PMSG at sponge removal and were inseminated 55 h after sponge removal. One-half of...

The interplay of environmental and genetic factors may lead to a spectrum of physiological and behavioral outcomes. How environmental stress factors interact with the diverse mouse genomes is still poorly understood and elucidating the underlying interactions requires specific stress models that can target integrated physiological systems. Here, we employ behavioral tests and whole-body plethys...

This paper presents the technical aspects, theoretical analysis, and comparisons of two new permanent magnet synchronous generator (PMSG) grid-interfaced models named PMSG boost and PMSG rectifierinverter. The exact feedback linearization (EFL) control scheme is used for the effective design and stability analysis of the aforementioned models. The complexity of the EFL control laws is discussed...

The efficiency of medroxyprogesterone acetate (MAP) and fluorogestone acetate (FGA) sponges with or without PGF2α (cloprostenol) for synchronizing estrous in non-lactating does was investigated during the natural breeding season. Does were treated for 11 days with 60 mg MAP (n = 38) or 40 mg FGA (n = 32) sponges. All does also received intramuscular injections of 500 IU PMSG. In addition, 19 an...

Superovulation induced by exogenous gonadotropin treatment (PMSG/hCG) increases the number of available oocytes in humans and animals. However, Superovulatory PMSG/hCG treatment is known to affect maternal environment, and these effects may result from PMSG/hCG treatment-induced oxidative stress. 2-Cys peroxiredoxins (2-Cys Prxs) act as antioxidant enzymes that protect cells from oxidative stre...

Hormonal influence resulting from serum gonadotropin was investigated by radiochemical activity studies of the degradation enzyme of monoamine oxidase catecholamines (MAo) in certain regions of the hypothalamus (area preoptica, corpus mamillare, infundibulum), which participates in the regulation of sheep sexual functioning, as well as in nucleus caudatus, in the hypophysis and epiphysis. We at...