background: helicobacter pylori may cause many gastrointestinal problems in developing countries such as iran. we aimed to analyze the cost- effectiveness and cost- utility of the test-and-treat and empirical treatment strategies in managing helicobacter pylori infection.            methods: this was a markov based economic evaluation. effectiveness was defined as the symptoms free numbers and ...

No previous report has demonstrated the relationship between Helico bacter pylori (HP) infection and gastric carcinogenesis in an experimental animal model. A total of 170 male Mongolian gerbils (MGs) were divided into nine groups (18 S n S 20 for each group). MGs of four groups were inoculated with HP before or after continuous A'-methyl-A'-nitrosourea (MNU) administration via the drinking wat...

seen in the primary care setting. We believe, however, that our findings would need to be assessed in the primary care setting before implementation is considered. Contributors: See bmj.com Funding: No pharmaceutical company or other commercial entity provided funding or other resources for the study. Competing interests: None declared. Ethical approval: The local ethics committee approved the ...

H. pylori infection is usually acquired in early childhood. Its role in gastrointestinal and extra intestinal complaints and serious consequences in adulthood make it as challenging issues. Despite different clinical presentations, in most children, the presence of H. pylori infection does not lead to clinically apparent disease, even when it causes chronic active gastritis. Some of most import...

Background: Until now, no study has been reported investigating the association between β-thalassemia minor and Helicobacter pylori (H. pylori) infection. This study was designed to compare H. pylori infection rate between β-thalassemia minor patients and healthy controls. Methods: A number of 100 β-thalassemia minor patients (50 males, 50 females) and 100 gender-matched healthy...

Objective(s): KRAS proto-oncogene mutation can be considered a diagnostic factor for treating various malignancies. Helicobacter pylori infection, a risk factor for stomach cancer, may cause DNA damage and genetic changes. The aim of the current study was to assess the association of gastric cancer and KRAS mutation, demographic factors, and H. pylori infection.<...